6-methoxy-3,4-dihydro-2H-isoquinolin-1-one

6-methoxy-3,4-dihydro-2H-isoquinolin-1-one - Names and Identifiers

Name	6-methoxy-3,4-dihydro-2H-isoquinolin-1-one
Synonyms	1-one 6-METHOXY-3,4-1(1H)-ISOQUINOLINONE 6-Methoxy-3,4-dihydro-2H-isoquinolin- 6-Methyl-3,4-dihydroisoquinolin-1(2H)-one 6-METHOXY-3,4-DIHYDROISOQUINOLIN-1(2H)-ONE 6-methoxy-3,4-dihydroisoquinolin-1(2H)-one 3,4-dihydro-6-methoxy-1(2H)-Isoquinolinone 6-METHOXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE 6-METHOXY-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE 6-methoxy-3,4-dihydro-2H-isoquinolin-1-one 1(2H)-Isoquinolinone, 3,4-dihydro-6-methoxy- 6-Methoxy-1,2,3,4-tetrahydroisoquinolin-1-one 6-(Methyloxy)-3,4-dihydro-1(2H)-isoquinolinone
CAS	22246-12-4
EINECS	1308068-626-2
InChI	InChI=1/C10H11NO2/c1-13-8-2-3-9-7(6-8)4-5-11-10(9)12/h2-3,6H,4-5H2,1H3,(H,11,12)

6-methoxy-3,4-dihydro-2H-isoquinolin-1-one - Physico-chemical Properties

Molecular Formula	C10H11NO2
Molar Mass	177.2
Density	1.159
Melting Point	136-138℃
Boling Point	439.8±45.0 °C(Predicted)
Flash Point	219.775°C
Vapor Presure	0mmHg at 25°C
pKa	14.77±0.20(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.549

6-methoxy-3,4-dihydro-2H-isoquinolin-1-one - Introduction

6-methoxy-3 is an organic compound with the chemical formula C10H11NO2.

Nature:
-Appearance: It is a white crystalline solid.
-Melting Point: about 160-162 ℃.
-Solubility: It dissolves well in common organic solvents (such as ethanol, ether and dichloromethane), but is almost insoluble in water.

Use:
-Drug synthesis: It is a commonly used intermediate compound used to synthesize various biologically active molecules or drugs.
-Chemical research: Due to its structural diversity and reactivity, it is also widely used in organic synthesis reactions, such as oxidation reactions, reduction reactions and hydrogenation reactions.

Method:
6-methoxy-3, phosphonium can be obtained by the following synthetic route:
1. First, polycondensation of 2-methoxyaldehyde benzene and acetic acid produces 1-methoxy-2-acetophenone.
2. Then, 1-methoxy-2-acetophenone is reacted with pyridine and sodium hydroxide to generate 2-methoxy-3-phenylacrylic acid sodium salt.
3. The sodium salt of 2-methoxy-3-phenylacrylic acid is reduced by hydrogenation reaction to produce 6-methoxy-3, and finally 6-methoxy-3 is produced.

Safety Information:
More detailed experimental data and studies are needed to make a comprehensive assessment of its specific safety and toxicity information. When using or handling this compound, it is recommended to take appropriate precautions and strictly follow safe operating procedures.

Last Update：2024-04-09 21:54:55