6-nitroindan-1-one
6-nitroindan-1-one
CAS: 24623-24-3
Molecular Formula: C9H7NO3
6-nitroindan-1-one - Names and Identifiers
| Name | 6-nitroindan-1-one |
| Synonyms | 6-NITROINDANONE 6-nitroindanone Einecs 246-366-7 6-nitroindan-1-one 6-nitro-1-indanone 6-NITRO-1-INDANONE 6-NITRO-INDAN-1-ONE 6-nitro-2,3-dihydroinden-1-one 2,3-dihydro-6-nitroinden-1-one 6-nitro-2,3-dihydro-1H-inden-1-one 2,3-Dihydro-6-nitro-1H-inden-1-one |
| CAS | 24623-24-3 |
| EINECS | 246-366-7 |
| InChI | InChI=1/C9H7NO3/c11-9-4-2-6-1-3-7(10(12)13)5-8(6)9/h1,3,5H,2,4H2 |
6-nitroindan-1-one - Physico-chemical Properties
| Molecular Formula | C9H7NO3 |
| Molar Mass | 177.16 |
| Density | 1.396±0.06 g/cm3(Predicted) |
| Melting Point | 71-73 °C |
| Boling Point | 332.0±31.0 °C(Predicted) |
| Flash Point | 169.8°C |
| Vapor Presure | 0.00015mmHg at 25°C |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.629 |
6-nitroindan-1-one - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R40 - Limited evidence of a carcinogenic effect |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. |
| Hazard Class | IRRITANT |
6-nitroindan-1-one - Introduction
6-nitroindan-1-one(6-nitroindan-1-one) is an organic compound with the chemical formula C9H5NO3. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 6-nitroindan-1-one is yellow crystal or yellow powder.
-Melting point: Its melting point is about 169-170°C.
-Solubility: It is soluble in organic solvents, such as ethanol, dimethylformamide and dichloromethane.
Use:
-Chemical synthesis: 6-nitroindan-1-one can be used as an organic synthesis intermediate. It can participate in various chemical reactions, such as fluorination, reduction and substitution reactions.
-Research use: It is used as a fluorescent probe, enzyme activity analysis and analytical reagent in scientific research.
Method:
The preparation method of 6-nitroindan-1-one can be carried out by the following steps:
1. 3-nitroresorcinol and acetoacetic anhydride are esterified to obtain benzenediol acetate.
2. Add sodium carbonate and alkali catalyst to the esterification product to carry out the ring-closing reaction to generate 6-nitroindan-1-one.
3. Finally, the pure product is obtained by crystallization purification or solvent extraction.
Safety Information:
there is no detailed information on the safety information of 6-nitroindan-1-one at present. Therefore, when handling this compound, we should strictly follow the laboratory safety operation procedures and comply with the relevant national safety management regulations. Laboratory personnel should wear appropriate personal protective equipment, such as laboratory gloves, goggles and protective clothing, to ensure safe operation. At the same time, the compound should be stored in a dry, well-ventilated place to prevent exposure to light and heat, and avoid contact with strong oxidants to avoid danger. If necessary, a comprehensive safety assessment should be conducted and a professional body should be consulted.
Nature:
-Appearance: 6-nitroindan-1-one is yellow crystal or yellow powder.
-Melting point: Its melting point is about 169-170°C.
-Solubility: It is soluble in organic solvents, such as ethanol, dimethylformamide and dichloromethane.
Use:
-Chemical synthesis: 6-nitroindan-1-one can be used as an organic synthesis intermediate. It can participate in various chemical reactions, such as fluorination, reduction and substitution reactions.
-Research use: It is used as a fluorescent probe, enzyme activity analysis and analytical reagent in scientific research.
Method:
The preparation method of 6-nitroindan-1-one can be carried out by the following steps:
1. 3-nitroresorcinol and acetoacetic anhydride are esterified to obtain benzenediol acetate.
2. Add sodium carbonate and alkali catalyst to the esterification product to carry out the ring-closing reaction to generate 6-nitroindan-1-one.
3. Finally, the pure product is obtained by crystallization purification or solvent extraction.
Safety Information:
there is no detailed information on the safety information of 6-nitroindan-1-one at present. Therefore, when handling this compound, we should strictly follow the laboratory safety operation procedures and comply with the relevant national safety management regulations. Laboratory personnel should wear appropriate personal protective equipment, such as laboratory gloves, goggles and protective clothing, to ensure safe operation. At the same time, the compound should be stored in a dry, well-ventilated place to prevent exposure to light and heat, and avoid contact with strong oxidants to avoid danger. If necessary, a comprehensive safety assessment should be conducted and a professional body should be consulted.
Last Update：2024-04-10 22:29:15
