6-phenylpyridin-3-amine - Names and Identifiers
6-phenylpyridin-3-amine - Physico-chemical Properties
Molecular Formula | C11H10N2
|
Molar Mass | 170.21 |
Density | 1.133±0.06 g/cm3(Predicted) |
Melting Point | 103 °C |
Boling Point | 341.9±22.0 °C(Predicted) |
Flash Point | 187.3°C |
Vapor Presure | 7.82E-05mmHg at 25°C |
pKa | 5.37±0.10(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.625 |
6-phenylpyridin-3-amine - Risk and Safety
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
Hazard Class | IRRITANT |
6-phenylpyridin-3-amine - Introduction
6-Phenyl-pyridin-3-ylamine, also known as N-(6-phenylpyridin-3-yl) methanamine, is an organic compound. Its chemical structure contains phenyl and pyridyl, with a certain degree of chemical reactivity.
Nature:
6-Phenyl-pyridin-3-ylamine is a white crystalline solid, soluble in some organic solvents such as alcohols and ethers, insoluble in water. Its melting point is about 165-170 degrees Celsius.
Use:
6-Phenyl-pyridin-3-ylamine is often used as a ligand in organic synthesis and is widely used in metal-organic chemistry and coordination chemistry. It can form complexes with metal ions for catalytic reactions and metal complexation chemistry studies.
Method:
The preparation of 6-phenyl-pyridin-3-ylamine is generally obtained by reacting pyridine with phenyl bromide. The specific step is to react pyridine and phenyl bromide in the presence of a base to generate 6-phenyl-pyridin-3-ylamine. The reaction is usually carried out in an ethanol or ether solvent.
Safety Information:
6-Phenyl-pyridin-3-ylamine is generally a relatively safe chemical when used and stored correctly. However, it is still an organic compound and should avoid contact with skin, eyes and inhalation of its dust. When in use, wear appropriate personal protective equipment such as gloves, glasses and laboratory coats. During handling and storage, attention should be paid to fire and explosion prevention. In case of accidental splashing or inhalation, rinse immediately with plenty of water and seek medical help.
Last Update:2024-04-09 15:17:51