60166-86-1

60166-86-1 - Names and Identifiers

Name	5-(methylsulfonyl)thiophene-2-carboxylic acid
Synonyms	(5-METHYLSULFONYL)THIOPHENE 2-Methylsulfonyl-5-thiophenecarboxylic acid 5-(METHYLSULFONYL)THIOPHENE-2-CARBOXYLIC ACID 5-(methylsulfonyl)thiophene-2-carboxylic acid 5-(METHANESULFONYL)THIOPHENE-2-CARBOXYLIC ACID 5-(methylsulphonyl)thiophene-2-carboxylic acid 5-(Methanesulfonyl)-2-thiophenecarboxylic acid 2-thiophenecarboxylic acid, 5-(methylsulfonyl)- 5-(Methylsulphonyl)-2-thenoic acid, 2-Carboxy-5-(methylsulphonyl)thiophene
CAS	60166-86-1
InChI	InChI=1/C6H6O4S2/c1-12(9,10)5-3-2-4(11-5)6(7)8/h2-3H,1H3,(H,7,8)

60166-86-1 - Physico-chemical Properties

Molecular Formula	C6H6O4S2
Molar Mass	206.24
Density	1.548±0.06 g/cm3(Predicted)
Melting Point	204 °C
Boling Point	485.6±45.0 °C(Predicted)
Flash Point	247.5°C
Vapor Presure	3.05E-10mmHg at 25°C
pKa	2.76±0.10(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.584

60166-86-1 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed R36 - Irritating to the eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37/39 - Wear suitable gloves and eye/face protection
HS Code	29349990

60166-86-1 - Introduction

5-(methylsulfonyl)thiophene-2-carboxylic acid is an organic compound with the chemical formula of C6H6O4S2. It is a white or slightly yellow solid powder. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White or yellowish solid powder
-Melting point: about 105-110°C
-Solubility: Soluble in some polar organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane (DCM), etc.
-Stability: Stable under normal storage conditions, avoid moisture and exposure to light

Use:
5-(methylsulfonyl)thiophene-2-carboxylic acid, as an organic synthesis intermediate, has some important applications:
-for the synthesis of new organic semiconductor materials
-for the preparation of heterocyclic derivatives
-For the preparation of biologically active compounds
-Used in areas such as drug synthesis

Preparation Method:
5-(methylsulfonyl)thiophene-2-carboxylic acid can be prepared by the following steps:
1. Sodium 2-thiobenzoate reacts with methanesulfonyl chloride under alkaline conditions to generate sodium 5-(methylsulfonyl)thiophene-2-carboxylic acid.
2. react 5-(methylsulfonyl)thiophene-2-carboxylic acid sodium with acid to generate 5-(methylsulfonyl)thiophene-2-carboxylic acid.

Safety Information:
The safety information about 5-(methylsulfonyl)thiophene-2-carboxylic acid needs further research and evaluation. Therefore, the following safety measures should be paid attention to when handling this compound:
-Avoid direct contact with skin and eyes
-Avoid inhaling its dust or gas
-Wear personal protective equipment such as lab gloves and goggles during operation
-Operate in a well-ventilated area or wear respiratory protection
-Comply with relevant laboratory safety procedures and operating instructions
-Follow local laws, regulations and rules when using or disposing of compounds

Last Update：2024-04-09 21:54:55