60166-98-5 - Names and Identifiers
Name | IOPAMIDOL RELATED COMPOUND A (50 MG) (N,N'-BIS-(1,3-DIHYDROXY-2-PROPYL)-5-AMINO-2,4,6-TRIIO-DOISO-PHTHALAMIDE)
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Synonyms | IopaMidol Related CoMpound A N,N′-Bis(1,3-dihydroxy-2-propyl)-5-amino-2,4,6-triiodoisophthalamide N,N′-Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-amino-2,4,6-triiodoisophthalamide 5-AMino-2,4,6-triiodisophthalsure-[N,N'-bis(2-hydroxy-1-hydroxyMethylethyl)]-diaMid 5-amino-1-N,3-N-bis(1,3-dihydroxypropan-2-yl)-2,4,6-triiodobenzene-1,3-dicarboxamide 5-AMino-N,N'-bis[2-hydroxy-1-(hydroxyMethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxaMide 5-Amino-N,N′-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodobenzene-1,3-dicarboxamide 5-Amino-N,N'-bis[2-hydroxy-1-(hydroxymethyl) ethyl]-2,4,6-triiodobenzene-1,3-dicarboxamide IOPAMIDOL RELATED COMPOUND A (50 MG) (N,N'-BIS-(1,3-DIHYDROXY-2-PROPYL)-5-AMINO-2,4,6-TRIIO-DOISO-PHTHALAMIDE)
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CAS | 60166-98-5
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60166-98-5 - Physico-chemical Properties
Molecular Formula | C14H18I3N3O6
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Molar Mass | 705.02 |
Density | 2.386±0.06 g/cm3(Predicted) |
Melting Point | >260°C (dec.) |
Boling Point | 688.7±55.0 °C(Predicted) |
Solubility | DMSO (Sparingly) |
Appearance | neat |
Color | White to Off-White |
pKa | 10.98±0.46(Predicted) |
Storage Condition | 2-8°C |
60166-98-5 - Risk and Safety
60166-98-5 - Introduction
IOPAMIDOL is a contrast agent widely used in medical imaging, which belongs to non-ionic contrast agents. The following is an introduction to compound A related to IOPAMIDOL:
The chemical name of compound A is N,N-bis (1,3-dihydroxy-2-propyl)-5-amino -2,4,6-triiodoisophthalamide (N,N-Bis(1,3-dihydroxy-2-propyl)-5-(amino)-2,4,6-triiodoisophthalamide), it has similar structure and properties to IOPAMIDOL.
Compound A is A colorless crystalline solid, soluble in water and organic solvents. It is a highly permeable X-ray contrast agent that can be used to enhance the image contrast of X-rays and CT scans.
The method for preparing compound A is mainly to obtain para-diiodoisophthalamide by reacting phthaloyl chloride and ethylenediamine, and then to generate the target product through an exothermic reaction.
When using compound A for imaging diagnosis, it is necessary to pay attention to its safety. Common side effects include allergic reactions, itchy skin, difficulty breathing, and low blood pressure. For patients with contrast agent allergy or hypothyroidism, renal insufficiency, hypertension, etc., compound A should be used with caution. At the same time, the dose should be reduced to reduce the risk of adverse reactions.
It should be emphasized that this information is for reference only, and the specific use should also follow the doctor's guidance and the relevant Pharmacopoeia regulations.
Last Update:2024-04-09 21:11:58