6020-87-7
Creatine Monohydrate
CAS: 6020-87-7
Molecular Formula: C4H11N3O3·H2O
6020-87-7 - Names and Identifiers
| Name | Creatine Monohydrate |
| Synonyms | Creatine Monohydrate Amidinosarcosine Monohydrate [(diaminomethylidene)(methyl)ammonio]acetate |
| CAS | 6020-87-7 |
| EINECS | 200-306-6 |
| InChI | InChI=1/C4H9N3O2/c1-7(4(5)6)2-3(8)9/h2H2,1H3,(H4,5,6,8,9) |
| InChIKey | MEJYXFHCRXAUIL-UHFFFAOYSA-N |
6020-87-7 - Physico-chemical Properties
| Molecular Formula | C4H11N3O3·H2O |
| Molar Mass | 149.15 |
| Melting Point | 292℃ |
| Boling Point | 271.6 °C at 760 mmHg |
| Water Solubility | 13 g/L (20℃) |
| Solubility | Slightly soluble in water, insoluble in ethanol and ether. |
| Appearance | Crystalline Powder |
| Color | White to yellow |
| Merck | 14,2568 |
| BRN | 907175 |
| PH | 6.9 (10g/l, H2O, 20℃) |
| Storage Condition | 2-8℃ |
| MDL | MFCD00071582 |
| Use | Widely used in food, beverage additives, etc |
6020-87-7 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| RTECS | MB7706000 |
6020-87-7 - Upstream Downstream Industry
| Downstream Products | Creatine phosphate disodium salt |
6020-87-7 - Reference
| Reference Show more | 1. Qiu Qinglian, Huang Cheng'an, Lin Li, etc. Evaluation of uncertainty in determination of creatine in Creatine powder by high performance liquid chromatography [J]. Journal of Food Safety and quality testing, 2019, 10(08):333-337. 2. Ye Shaowen, Gao Zhiyan, Su Zhaolun. Determination of creatine, creatinine and dicyandiamide in Creatine powder by HPLC [J]. Journal of Food Safety and quality testing, 2020,11(23):8721-8725. 3. [IF = 7.514] Xiaoli Cheng et al." in freshwater."Food Chem. 2021 Aug;354:129498 4. [IF=3.718] Juan Tian et al."Role of creatine supplementation on the myofiber characteristics and muscle protein synthesis of grass carp (Ctenopharyngodon idellus)."BRITISH JOURNAL OF NUTRITION. 2022 May;:1-45 |
6020-87-7 - Introduction
Slightly soluble in water, insoluble in ethanol and ether, solubility in water: 13G/L water (20°C),1g/9L alcohol.
Last Update：2022-10-16 17:26:57
6020-87-7 - Introduction
Introduction Creatine in the human body is formed by amino acids during the chemical process in the liver, and then sent from the blood to muscle cells, where it is converted into creatine. The movement of human muscles is to break down adenosine triphosphate (ATP) to provide energy. Creatine can automatically adjust the water entering the muscle, so that the cross-sectional muscle expansion, thereby increasing the explosive power of the muscle.
Physiological effects
Creatine in the human body is formed by amino acids during the chemical process in the liver, and then it is sent from the blood to muscle cells, where it is converted into creatine salt. The movement of human muscles is to break down adenosine triphosphate (ATP) to provide energy. Creatine can automatically adjust the water entering the muscle, so that the cross-sectional muscle expansion, thereby increasing the explosive power of the muscle. A large number of in vivo and in vitro experiments have confirmed that creatine has multiple effects on the human body:
1. Increase creatine content in skeletal muscle and increase energy reserve
2. regulate glucose metabolism pathway and reduce lactic acid production
3. Increase intramuscular glycogen reserve
4. Increase antioxidant function
Last Update：2024-04-10 22:29:15
6020-87-7 - Use
Use
The synthetic creatine can be used as a nutritional supplement to promote the skeletal muscles to adapt to strenuous exercise and combat fatigue of weak individuals; it can also be used to prepare drugs for the treatment of heart disease and respiratory insufficiency; prepare pharmaceutical preparations containing human growth hormone; and It can be used to compose a new health food, which has the effects of anti-aging and restoring youth. Since creatine is not a hormone, it does not cause any interference or damage to the human endocrine system, and will not cause people to have drug-dependent or physiological side effects, so creatine supplements have become very popular in recent years. Creatine exists in fish and meat, but the quantity is very small. It is difficult to obtain all of it from food to reach the daily intake of each person that is helpful for muscle growth. A large number of studies have reported that creatine supplementation with monohydrate can increase the content of creatine in skeletal muscle.
Creatine can be converted into creatine phosphate under the action of creatine kinase, thereby increasing the energy supply of creatine phosphate. Changes in creatine metabolism induced by supplemental feeding of creatine may change the body's original growth and development and meat quality. Although there are few reports on the application of creatine in livestock and poultry production, and the results are quite different, it provides a new and effective method for improving the quality of livestock and poultry meat and shows great application potential.
Chemical properties White crystal or crystalline powder, slightly soluble in water, insoluble in ethanol and ether.
Use biochemical research
Usage Product Description: Pharmaceutical Raw Materials and Health Products Additives. It can inhibit the generation of muscle fatigue factors, reduce fatigue and tension, restore physical fitness, accelerate human protein synthesis, make muscles stronger, enhance muscle elasticity, reduce cholesterol, blood lipids, and blood sugar levels, improve muscle atrophy in middle-aged and elderly people, and delay aging
It is widely used in food, beverage, additive, etc. Pharmaceutical raw materials and health products additives. It can inhibit the generation of muscle fatigue factors, reduce fatigue and tension, restore physical fitness, accelerate human protein synthesis, make muscles stronger, enhance muscle elasticity, reduce cholesterol, blood lipids, and blood sugar levels, improve muscle atrophy in middle-aged and elderly people, and delay aging
Last Update：2024-04-10 22:29:15
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