603-54-3
1,1-diphenylurea
CAS: 603-54-3
Molecular Formula: C13H12N2O
603-54-3 - Names and Identifiers
| Name | 1,1-diphenylurea |
| Synonyms | 1,1-diphenylurea Asym-Diphenylurea |
| CAS | 603-54-3 |
| EINECS | 210-048-6 |
603-54-3 - Physico-chemical Properties
| Molecular Formula | C13H12N2O |
| Molar Mass | 212.25 |
| Density | 1.2760 |
| Melting Point | 189°C |
| Boling Point | 352.09°C (rough estimate) |
| pKa | 15.11±0.50(Predicted) |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| Refractive Index | 1.6920 (estimate) |
603-54-3 - Introduction
1,1-diphenylurea (1,1-diphenylurea) is an organic compound with the chemical formula C13H12N2O. It has the following properties:
1. Physical properties: 1,1-diphenylurea is a white to light yellow crystalline solid, which is a combustible substance at room temperature. It has a melting point of about 162-166 degrees Celsius and a boiling point of about 230 degrees Celsius. Its solubility is lower than that of water, but it can be dissolved in many organic solvents.
2. Chemical properties: 1,1-diphenylurea is a relatively stable compound, not easy to decompose. It can be accelerated by the action of acid or alkali decomposition. It can be hydrolyzed by sodium hydroxide and potassium hydroxide solutions to the corresponding urea and aniline.
Use:
1,1-diphenylurea has some application value, mainly including the following aspects:
1. It can be used as a synthetic intermediate in the field of medicine, especially in the preparation of terephthalic acid derivatives and antitumor drugs play an important role.
2. It can also be used as an intermediate for dyes and pigments, especially synthetic color dyes.
Preparation Method:
1,1-diphenylurea can be obtained by reacting aniline with dichloromethane. The specific synthesis method is to add aniline and dichloromethane into the reaction bottle, then add a certain amount of cuprous chloride and sodium nitrite, after a period of reaction, add sodium hydroxide solution at low temperature, filter, wash and dry, you can end up with 1,1-diphenylurea.
Safety Information:
1,1-diphenylurea is generally relatively safe under normal conditions of use. However, it is a combustible substance and care should be taken to avoid contact with open flames and high temperatures. Wear protective glasses and gloves during operation to avoid inhalation or skin contact. At the same time, it should be operated in a well-ventilated environment to prevent damage to the human body.
In General, 1,1-diphenylurea is an important organic compound with a variety of applications, but it is necessary to pay attention to safe operation during use.
1. Physical properties: 1,1-diphenylurea is a white to light yellow crystalline solid, which is a combustible substance at room temperature. It has a melting point of about 162-166 degrees Celsius and a boiling point of about 230 degrees Celsius. Its solubility is lower than that of water, but it can be dissolved in many organic solvents.
2. Chemical properties: 1,1-diphenylurea is a relatively stable compound, not easy to decompose. It can be accelerated by the action of acid or alkali decomposition. It can be hydrolyzed by sodium hydroxide and potassium hydroxide solutions to the corresponding urea and aniline.
Use:
1,1-diphenylurea has some application value, mainly including the following aspects:
1. It can be used as a synthetic intermediate in the field of medicine, especially in the preparation of terephthalic acid derivatives and antitumor drugs play an important role.
2. It can also be used as an intermediate for dyes and pigments, especially synthetic color dyes.
Preparation Method:
1,1-diphenylurea can be obtained by reacting aniline with dichloromethane. The specific synthesis method is to add aniline and dichloromethane into the reaction bottle, then add a certain amount of cuprous chloride and sodium nitrite, after a period of reaction, add sodium hydroxide solution at low temperature, filter, wash and dry, you can end up with 1,1-diphenylurea.
Safety Information:
1,1-diphenylurea is generally relatively safe under normal conditions of use. However, it is a combustible substance and care should be taken to avoid contact with open flames and high temperatures. Wear protective glasses and gloves during operation to avoid inhalation or skin contact. At the same time, it should be operated in a well-ventilated environment to prevent damage to the human body.
In General, 1,1-diphenylurea is an important organic compound with a variety of applications, but it is necessary to pay attention to safe operation during use.
Last Update：2024-04-09 21:11:58
