Molecular Formula | C4H6ClN3O |
Molar Mass | 147.56294 |
Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
Appearance | Powder |
Storage Condition | 2-8℃ |
Use | the use of wild indigo as a drug for the treatment of ischemic stroke has the following beneficial effects: (1) without reducing blood glucose, wild indigo can significantly improve the neurological dysfunction, reduce the volume of cerebral infarction and the rate of cell apoptosis in the middle cerebral artery occlusion model (MCAO) Mice. (2) can reduce brain edema and other brain tissue damage; (3) can reduce oxidative stress lipid peroxidation and promote the recovery of oxygen free radical scavenger content, significantly inhibited the expression of NR2B protein and mRNA in brain tissue after ischemia, promoted the phosphorylation of CREB and REK and the expression of ERK and CREB mRNA. |