6048-29-9

6048-29-9 - Names and Identifiers

Name	Phenacyltriphenylphosphonium bromide
Synonyms	NSC 6743 phenacyltriphenyl-phosphoniubromide Phenacyltriphenylphosphonium bromide PHENACYLTRIPHENYLPHOSPHONIUM BROMIDE Phosphonium, phenacyltriphenyl-, bromide BENZOYLMETHYLTRIPHENYLPHOSPHONIUM BROMIDE (2-oxo-2-phenylethyl)triphenylphosphoniuM broMide (2-oxo-2-phenylethyl)(triphenyl)phosphonium bromide Phosphonium, (2-oxo-2-phenylethyl)triphenyl-, bromide
CAS	6048-29-9
EINECS	227-945-3
InChI	InChI=1/C26H22OP.BrH/c27-26(22-13-5-1-6-14-22)21-28(23-15-7-2-8-16-23,24-17-9-3-10-18-24)25-19-11-4-12-20-25;/h1-20H,21H2;1H/q+1;/p-1

6048-29-9 - Physico-chemical Properties

Molecular Formula	C26H22BrOP
Molar Mass	461.33
Melting Point	265-268 °C (dec.) (lit.)
Solubility	very faint turbidity in Methanol
Appearance	solid
Color	White to Light yellow to Light orange
BRN	3642554
Storage Condition	Inert atmosphere,Room Temperature
Sensitive	Hygroscopic
MDL	MFCD00011920

6048-29-9 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3
RTECS	TA2400000
HS Code	29310099

6048-29-9 - Introduction

Phenacyltriphenylphosphonium bromide is an organic compound with the chemical formula C27H20BrP. The following is a description of its nature, use, formulation and safety information:

Nature:
Phenacyltriphenylphosphonium bromide is a colorless crystalline solid. It is soluble in organic solvents such as ethanol, chloroform and dichloromethane, but insoluble in water. The compound has a strong odor.

Use:
Phenacyltriphenylphosphonium bromide have a variety of applications in chemical synthesis. It is often used as an activating reagent, which can initiate the condensation reaction of aldehydes and ketones, and is an important reagent for the synthesis of α,β-unsaturated ketones and α,β-imides. In addition, it can also be used as a catalyst for drug synthesis, coordination chemistry and organic synthesis reactions.

Preparation Method:
Phenacyltriphenylphosphonium bromide can be prepared by the reaction of triphenylphosphonium bromide and benzophenone. In the reaction, triphenylphosphonium bromide acts as a catalyst as an in-situ generator of bromide ions.

Safety Information:
Take appropriate safety precautions when using and handling Phenacyltriphenylphosphonium bromide. It should avoid contact with skin, eyes and mucous membranes, and avoid inhaling its particles or vapors. Wear protective gloves, safety glasses and protective mask for operation. Keep well ventilated during use, and clean the work area thoroughly after operation. In addition, Phenacyltriphenylphosphonium bromide should be stored properly and kept away from ignition and oxidizing agents.

Last Update：2024-04-09 20:52:54