608-31-1
2,6-Dichloroaniline
CAS: 608-31-1
Molecular Formula: C6H5Cl2N
608-31-1 - Names and Identifiers
| Name | 2,6-Dichloroaniline |
| Synonyms | 2,6-DCA 2,6-Dichloroaniline Clonidine EP Impurity C 2,6-dichlorobenzenamine 2,6-Dichlorophenylamine 2,6-Dichlorobenzene amine 2,6-Dichlorobenzene amide |
| CAS | 608-31-1 |
| EINECS | 210-160-5 |
| InChI | InChI=1/C6H5Cl2N/c7-4-2-1-3-5(8)6(4)9/h1-3H,9H2 |
608-31-1 - Physico-chemical Properties
| Molecular Formula | C6H5Cl2N |
| Molar Mass | 162.02 |
| Density | 1,275 g/cm3 |
| Melting Point | 36-38 °C (lit.) |
| Boling Point | 228 °C |
| Flash Point | >230°F |
| Water Solubility | 1.6 g/L (20 ºC) |
| Solubility | 1.6g/l |
| Appearance | Crystalline Solid |
| Color | White to brown |
| BRN | 775084 |
| pKa | 0.71±0.10(Predicted) |
| Storage Condition | Store below +30°C. |
| Refractive Index | 1.6000 (estimate) |
| Physical and Chemical Properties | Needle-like crystals were obtained from an aqueous solution of ethanol. Melting point 39-40 °c. Soluble in ethanol, ether, insoluble in water. |
| Use | Used as intermediates in pharmaceuticals, pesticides and dyes |
608-31-1 - Risk and Safety
| Risk Codes | R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R33 - Danger of cumulative effects R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S28 - After contact with skin, wash immediately with plenty of soap-suds. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S28A - |
| UN IDs | UN 3442 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | CX9862655 |
| FLUKA BRAND F CODES | 8 |
| TSCA | T |
| HS Code | 29214210 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
| Packing Group | II |
608-31-1 - Upstream Downstream Industry
| Raw Materials | Fluoroboric acid |
608-31-1 - Nature
Open Data Verified Data
needle-like crystals were obtained from an aqueous ethanol solution. 39~40 ° C melting point, insoluble in water, soluble in ethanol and ether.
Last Update：2024-01-02 23:10:35
608-31-1 - Preparation Method
Open Data Verified Data
- p-aminobenzenesulfonamide was obtained by chlorination and hydrolysis.
- p-aminobenzoate was obtained by chlorination, hydrolysis and decarboxylation.
- p-aminobenzoic acid method.
- 2, 6-chlorobenzoic acid is obtained by acylation and reaction with hydroxylamine to remove carbon dioxide.
- The cyclohexanone method is obtained by chlorination, ammonification and dehydrogenation.
Last Update：2022-01-01 10:51:32
608-31-1 - Use
Open Data Verified Data
The pharmaceutical industry is used for the synthesis of quinonic acid antibacterial drugs lomefloxacin, uric acid and clonidine; The pesticide industry is used for the synthesis of herbicides and fungicides.
Last Update：2022-01-01 10:51:31
608-31-1 - Safety
Open Data Verified Data
- it can burn when exposed to open flame, and is decomposed into toxic smoke by high heat. Harmful by inhalation or absorption through the skin.
- the use of white iron drum, coated with plastic film packaging, storage should be heat, moisture.
Last Update：2022-01-01 10:51:32
608-31-1 - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| uses | the pharmaceutical industry is used to synthesize lomefloxacin, liuric acid and clonidine, the antimicrobials of quinone acids. The pesticide industry is used to synthesize herbicides and fungicides. Used as a pharmaceutical intermediate, used for the synthesis of ofloxacin, clonidine, etc., and also a dye intermediate Used as an intermediate for medicine, pesticides and dyes |
| production method | 1. it is obtained by chlorination of p-aminobenzenesulfonamide with concentrated hydrochloric acid and hydrolysis of sulfuric acid. 2. p-aminobenzoate method is obtained by chlorination, hydrolysis and decarboxylation. 3. p-carbamate method. 4.2, 6-dichlorobenzoic acid method is obtained by acylation, reaction with hydroxylamine, and removal of carbon dioxide. 5. Cyclohexanone method is obtained by chlorination, ammoniation and dehydrogenation. |
Last Update：2024-04-09 20:52:54
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Product Name: Clonidine Impurity 3(Clonidine EP Impurity C) Visit Supplier Webpage Request for quotationCAS: 608-31-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: 2,6-Dichloroaniline Request for quotationCAS: 608-31-1
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: 2,6-Dichloroaniline Request for quotationCAS: 608-31-1
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Spot supply
Product Name: 2,6-Dichloroaniline Request for quotationCAS: 608-31-1
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
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Raw Materials for 608-31-1