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616204-22-9

Argireline

CAS: 616204-22-9

Molecular Formula: C34H60N14O12S

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616204-22-9 - Names and Identifiers

Name Argireline
Synonyms Reproage
Argireline
Anti-Wrinkle Multi-Peptides
Ac-Glu-Glu-Met-Glu-Arg-Arg-NH2
Argireline,Acetyl hexapeptide-3, BR
N-Acetyl-L-alpha-glutamyl-L-alpha-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-argininamide
Argireline acetate Ac-Glu-Glu-Met-Arg-Arg-NH2
CAS 616204-22-9
EINECS 1592732-453-0
InChI InChI=1/C34H60N14O12S/c1-17(49)43-20(8-11-25(51)52)29(57)47-22(9-12-26(53)54)31(59)48-23(13-16-61-2)32(60)46-21(7-10-24(35)50)30(58)45-19(6-4-15-42-34(39)40)28(56)44-18(27(36)55)5-3-14-41-33(37)38/h18-23H,3-16H2,1-2H3,(H2,35,50)(H2,36,55)(H,43,49)(H,44,56)(H,45,58)(H,46,60)(H,47,57)(H,48,59)(H,51,52)(H,53,54)(H4,37,38,41)(H4,39,40,42)/t18-,19-,20-,21-,22-,23-/m0/s1
InChIKey RJZNPROJTJSYLC-LLINQDLYSA-N

616204-22-9 - Physico-chemical Properties

Molecular FormulaC34H60N14O12S
Molar Mass889
Density1.54
Solubility water soluble
Appearancelyophilized solid
Colorwhite
pKa4.43±0.10(Predicted)
Storage Condition-20°C
Refractive Index1.66
In vitro study The incubation of Argireline solution in different concentrations with human embryonic kidney HEK-293 (IC 50 of 34.862 μM) and neuroblastoma IMR-32 cells (IC 50 of 68.458 μM)) for 48 h have dose dependent antiproliferative effect. Argireline solution incubated in different concentrations with HSF has a dose-dependent antiproliferative effect on those cells. Cellular proliferation is not effected in Argireline low concentration.
In vivo study Argireline is applied to the aged mice twice daily for 6 weeks. There is an improvement in the histological structure of skin tissue in the aged mice; the amount of type I collagen fibers increased, while that of type III collagen fibers decreased. Argireline could improve the histological structure of skin tissue and rejuvenate the aging skin.

616204-22-9 - Risk and Safety

WGK Germany2
616204-22-9
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Shanxi Weier Chemical Co.,Ltd
Spot supply
Product Name: Argireline Request for quotation
CAS: 616204-22-9
Tel:
Email: Anna@weierchemical.com
WhatsApp: +8618532131551
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: Argireline Request for quotation
CAS: 616204-22-9
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Cellmano Biotech Limited
Product Name: Acetyl Hexapeptide-8 Request for quotation
CAS: 616204-22-9
Tel: 008655165326643
Email: qilin@cellmano.com
Mobile: 008618156095617
QQ: 1761863581 Click to send a QQ messageSend QQ message
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616204-22-9
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