Name | Ethyl methanesulfonate |
Synonyms | EMS B 1528 CB 1528 ent26396 ENT 26396 Ethyl methanesulfonate Ethyl ester of methylsulfonic acid Ethyl ester of methanesulfonic acid Ethyl ester of methylsulphonic acid Ethyl ester of methanesulphonic acid |
CAS | 62-50-0 |
EINECS | 200-536-7 |
InChIKey | PLUBXMRUUVWRLT-UHFFFAOYSA-N |
Molecular Formula | C3H8O3S |
Molar Mass | 124.16 |
Density | 1.206 g/mL at 20 °C |
Boling Point | 85-86 °C/10 mmHg (lit.) |
Flash Point | 100 °C |
Water Solubility | Miscible with water. |
Solubility | 50-100g/l |
Vapor Presure | 0.27 hPa (25 °C) |
Appearance | liquid |
Color | Colourless to Pale Yellow |
Merck | 14,3827 |
BRN | 773969 |
Storage Condition | 2-8°C |
Stability | Stable. Combustible. Incompatible with water, alkalies, oxidizing agents. |
Sensitive | Moisture Sensitive |
Refractive Index | n20/D 1.418(lit.) |
Physical and Chemical Properties | Colorless transparent oily liquid. Boiling point 213-213.5 ℃,85-86 ℃(1.33kPa), relative density 1.1452(22/4 ℃). Soluble in ether, ethanol, chloroform, water-soluble. |
Use | Use as a strain mutagen, as well as organic synthesis and cancer research. |
Hazard Symbols | T - Toxic |
Risk Codes | R46 - May cause heritable genetic damage R22 - Harmful if swallowed R40 - Limited evidence of a carcinogenic effect R36/37/38 - Irritating to eyes, respiratory system and skin. R45 - May cause cancer |
Safety Description | S53 - Avoid exposure - obtain special instructions before use. S23 - Do not breathe vapour. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
UN IDs | 2810 |
WGK Germany | 3 |
RTECS | PB2100000 |
FLUKA BRAND F CODES | 10-21 |
TSCA | Yes |
HS Code | 29041000 |
Hazard Class | 6.1 |
Packing Group | II |
Author:
Yang Mao pure , Zhao Geng Mao , Wang Changhai
Abstract:
in order to improve the oil-producing ability of Nitzschia cesterium and to obtain a mutant strain with high oil content, ethyl methanesulfonate (EMS) was used to chemically mutagenize the strain, and its biological effects were investigated. The results showed that EMS had a good mutagenic effect on the small Crescent, after treated by 0.1 mol/L and 0.05 mol/L EMS, the mutant algal strains YA and YB with strong oil production ability were obtained, respectively, under the same culture conditions, the relative contents of chlorophyll a, carotenoid, protein, soluble sugar and oil in the unit volume cells of the two mutant algae increased by 30.05% and 25.77%, respectively, compared with the control group, 22.15% and 19.26%, 9.06% and 8.27%, 48.25% and 45.48%, 44.06% and 12.86%.
Key words:
microalgae Small Crescent rhomboid algae (Nitzschia closterium) mutagenesis ethyl methanesulfonate Grease
DOI:
CNKI:SUN:HYKX.0.2015-01-002
cited:
year:
2015
Author:
Abstract:
Abstract:
Key words:
ethyl methanesulfonate rice Young spike
cited:
year:
1989
(IARC) carcinogen classification | 2B (Vol. 7, Sup 7) 1987 |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
use | as a mutagen for strains, as well as research on organic synthesis and cancer. |
Production method | The methyl sulfonyl chloride obtained by the reaction of dimethyl sulfate and sodium thiosulfate is esterified with ethanol to obtain ethyl methyl sulfonate. |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |