623145-57-3 - Names and Identifiers
623145-57-3 - Physico-chemical Properties
Molecular Formula | C10H8N4O4
|
Molar Mass | 248.19 |
Density | 1.58±0.1 g/cm3(Predicted) |
Melting Point | 220-221°C |
Solubility | DMSO (Slightly) |
Appearance | neat |
Color | Pale Yellow |
pKa | 7.76±0.10(Predicted) |
Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
623145-57-3 - Risk and Safety
623145-57-3 - Introduction
2-NP-AHD(2-Nitrophenylaminohexane) is an organic compound with the chemical formula C12H19N3O2 and a molecular weight of 233.30g/mol. It is a pale yellow solid, soluble in some organic solvents such as ethanol and dichloromethane.
2-NP-AHD is mainly used as a reducing agent in organic synthesis. It can be used to reduce carbonyl containing compounds such as ketones, aldehydes and the like to convert them to the corresponding alcohols. It can also be used to reduce nitrites to form the corresponding amines. Due to its strong reducibility, it needs to be operated with caution.
The method for preparing 2-NP-AHD can be obtained by reacting 2-nitrotoluene with adipaldehyde. First, 2-nitrotoluene and adipaldehyde are subjected to a condensation reaction in the presence of sodium carbonate to produce 1-[2-(hexylamino) phenyl] acetone as an intermediate. The intermediate is then hydrolyzed under acidic conditions of sulfuric acid to give the final product 2-NP-AHD.
When using 2-NP-AHD, you need to pay attention to its safety information. It is a toxic substance that can cause damage to the human body, such as irritation to the eyes and respiratory system. Wear protective goggles and gloves during operation, and ensure that it is carried out in a well-ventilated place. At the same time, avoid contact with strong oxidants or combustibles to prevent fire or explosion. When storing, it should be kept in a dry, cool, ventilated place, away from fire and flammable materials. If ingested, inhaled or in contact with skin, seek medical attention immediately.
Last Update:2024-04-10 22:29:15