627-03-2
Ethoxyacetic acid
CAS: 627-03-2
Molecular Formula: C4H8O3
627-03-2 - Names and Identifiers
| Name | Ethoxyacetic acid |
| Synonyms | ethoxyacetate 2-ethoxyacetate ethoxy-aceticaci Ethoxyacetic acid Ethoxyethanoicacid 2-ethoxyaceticacid Aceticacid,ethoxy- 2-Ethoxyacetic acid Glycolic ethyl ether O-Ethylglycolic acid |
| CAS | 627-03-2 |
| EINECS | 210-978-2 |
| InChI | InChI=1/C4H8O3/c1-2-7-3-4(5)6/h2-3H2,1H3,(H,5,6)/p-1 |
627-03-2 - Physico-chemical Properties
| Molecular Formula | C4H8O3 |
| Molar Mass | 104.1 |
| Density | 1.102 g/mL at 25 °C (lit.) |
| Boling Point | 97-100 °C/11 mmHg (lit.) |
| Flash Point | 208°F |
| Water Solubility | soluble |
| Vapor Presure | 0.0958mmHg at 25°C |
| Appearance | Liquid |
| Color | Clear colorless to light yellow |
| BRN | 1743037 |
| pKa | 3.65(at 18℃) |
| Storage Condition | 2-8°C |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| Refractive Index | n20/D 1.419(lit.) |
| MDL | MFCD00004310 |
| Physical and Chemical Properties | Character: colorless liquid. boiling point 206~207 ℃ relative density 1.1021 refractive index 1.417 solubility, alcohols and ethers. |
| Use | For organic synthesis and biochemical research |
627-03-2 - Risk and Safety
| Risk Codes | 34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 3265 8/PG 2 |
| WGK Germany | 3 |
| RTECS | AH3600000 |
| TSCA | Yes |
| HS Code | 29189900 |
| Hazard Note | Irritant |
| Hazard Class | 8 |
| Packing Group | III |
627-03-2 - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| biological activity | ethoxyacemic acid is an endogenous metabolite. |
| uses | for organic synthesis and biochemical research organic synthesis intermediates. |
| production method | the solution of chloroacetic acid and anhydrous ethanol was added to the sodium ethoxide-ethanol solution successively, after heating slowly for 10min, the excess ethanol was distilled off with direct water vapor, the aqueous solution was cooled, concentrated hydrochloric acid was added, and sodium chloride was filtered off. The filtrate was extracted with ether, the ether was distilled off from the extract, and then distilled under reduced pressure to obtain ethoxyacetic acid in a yield of 2.27 by collecting a fraction at 109-111 ° C. (2.40-74% kPa). |
Last Update：2024-04-09 15:16:52
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