628330-15-4 - Names and Identifiers
628330-15-4 - Introduction
methyl 2-(3-(benzyloxy)phenyl)-2-methylpropanoate, chemical formula C17H18O3, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: It is a colorless liquid.
-Density: About 1.12 g/mL.
-Melting point: Its melting point range is about -25 to -20 ° C.
-Boiling point: Its boiling point is about 344 ° C.
-Solubility: It is soluble in many organic solvents, such as ethanol, dimethylformamide and ethers.
Use:
- methyl 2-(3-(benzyloxy)phenyl)-2-methylpropanoate can be used as an organic synthesis intermediate for the synthesis of other compounds.
-It can also be used in the field of medicine, such as synthetic drugs or active ligands.
Method:
methyl 2-(3-(benzyloxy)phenyl)-2-methylpropylanoate can be synthesized by the following steps:
1. Phenylcarbinol is methylated by reacting phenylcarbinol with an active methylating reagent to obtain benzyl carbinol.
2. React benzyl methanol with benzyl magnesium bromide to dehalogenate benzyl methanol and undergo a substitution reaction with benzyl magnesium bromide to obtain 2-(benzyl) benzyl methanol.
3. Etherification of 2-(benzyl) benzylmethanol with a hydroxyl-reactive compound (such as sodium hydroxide) gives methyl 2-(3-(benzyloxy)phenyl)-2-methylpropylanoate.
Safety Information:
- methyl 2-(3-(benzyloxy)phenyl)-2-methylpropanoate should be kept away from heat, fire and oxygen.
-When using, please wear appropriate personal protective equipment, such as gloves and goggles.
-Observe all relevant safety measures and operating procedures when using or storing.
Last Update：2024-04-09 02:00:52