Molecular Formula | C7H6BrNO2 |
Molar Mass | 216.03 |
Density | 1.759±0.06 g/cm3(Predicted) |
Melting Point | 241-245°C(lit.) |
Boling Point | 316.6±32.0 °C(Predicted) |
pKa | 7.79±0.18(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Hazard Symbols | Xn - Harmful |
Risk Codes | R22 - Harmful if swallowed R43 - May cause sensitization by skin contact |
Safety Description | S28 - After contact with skin, wash immediately with plenty of soap-suds. S36/37 - Wear suitable protective clothing and gloves. |
WGK Germany | 3 |
RTECS | VN7000000 |
Application | 5-bromosalicylamide is an amide organic substance, which can be used as an intermediate in pharmaceutical synthesis. |
preparation method | in a 100mL round bottom flask, 1.5g(0.011mol) salicylamide is stirred and dissolved in 21.9mL glacial acetic acid, 0.556mL(0.011mol) glacial acetic acid solution of liquid bromine is slowly added dropwise at room temperature, stirred for reaction, TLC tracks the reaction to the end point, the product is poured into cold water, and a large amount of white solid is precipitated. |