Name | ADENOSINE-2',3'-CYCLIC PHOSPHATE |
Synonyms | 2',3'-cyclic AMP 2',3'-cAMP TriethylaMMoniuM Salt ADENOSINE-2',3'-CYCLIC PHOSPHATE adenosine cyclic 2',3'-(hydrogen phosphate) 2',3'-Cyclic Adenosine Monophosphate TriethylaMMoniuM Salt Adenosine Cyclic 2',3'-Monophosphate TriethylaMMoniuM Salt ADENOSINE-2',3'-CYCLIC PHOSPHATE, DICYCLOHEXYLGUANIDINIUM SALT Adenosine Cyclic 2',3'-(Hydrogen Phosphate) TriethylaMMoniuM Salt |
CAS | 634-01-5 |
EINECS | 211-202-5 |
Molecular Formula | C10H12N5O6P |
Molar Mass | 329.21 |
Melting Point | 208-213°C |
Solubility | Methanol (Slightly), Water (Slightly) |
Appearance | Solid |
Color | Pale Yellow |
Storage Condition | -20°C Freezer, Under Inert Atmosphere |
overview | ring nucleotides are important second messengers in cells and participate in the regulation of various signal transduction pathways in cells. The second messengers known to be found include cyclic adenosine monophosphate (3 ′,5 ′-cAMP), cyclic guanosine monophosphate (3 ′,5 ′-cGMP), cyclic cytidine monophosphate (3 ′,5 ′-cCMP), cyclic uridine monophosphate (3 ′,5 ′-cUMP), cyclic diguanylate (c-di-GMP), cyclic diadenosine (c-di-AMP) and cyclic guanosine adenosine (cGAMP). In addition to the second messenger of the ring nucleotide class that has been discovered above, in 2009 Edwin et al. also discovered adenosine -2 ',3'-cyclic phosphate (2 ',3') in human kidney cells for the first time.-cAMP), and then people found the presence of adenosine -2 ',3'-cyclic phosphate in mammalian brain and other tissue cells. The researchers also detected adenosine -2 ',3'-cyclic monophosphate and guanosine -2 ',3'-cyclic phosphate (2 ',3'-cGMP) from plant cells, cytidine -2 ',3'-cyclic phosphate (2 ',3'-cCMP) and uridine -2 ',3'-cyclic monophosphate (2 ′,3 '-cUMP). The existing research results show that these four 2 ′,3 ′-cyclic nucleoside monophosphates may represent another new type of second messenger of biological cells. As 2 ′,3 ′-cyclic nucleoside monophosphate has attracted more and more attention, its demand for scientific research and medicine is also increasing. At present, the preparation of 2 ′,3 ′-ring nucleoside monophosphoric acid adopts chemical synthesis methods, and there is no biological preparation method. The production of 2 ′,3 ′-cyclic nucleoside monophosphate by chemical synthesis has low yield and high price, which limits its development and application to a certain extent. |