63558-65-6
4-Chloro-5-iodo-pyrimidine
CAS: 63558-65-6
Molecular Formula: C4H2ClIN2
63558-65-6 - Names and Identifiers
| Name | 4-Chloro-5-iodo-pyrimidine |
| Synonyms | 5-Iodo-4-Chloropyrimidine 4-Chloro-5-iodopyrimidine 4-Chloro-5-iodo-pyrimidine Pyrimidine, 4-chloro-5-iodo- 4-HYDROXYBENZENSULFONIC ACID SODIUM |
| CAS | 63558-65-6 |
| InChI | InChI:1S/C4H2ClIN2/c5-4-3(6)1-7-2-8-4/h1-2H |
63558-65-6 - Physico-chemical Properties
| Molecular Formula | C4H2ClIN2 |
| Molar Mass | 240.43 |
| Density | 2.187±0.06 g/cm3(Predicted) |
| Melting Point | 63-65 °C |
| Boling Point | 275.0±20.0 °C(Predicted) |
| Flash Point | 120.125 °C |
| pKa | -1.35±0.16(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
63558-65-6 - Introduction
It is an organic compound with the chemical formula of C4H2ClIN2. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: It is a white to light yellow crystalline powder.
-Melting point: Its melting point is about 168-171 degrees Celsius.
-Solubility: It has good solubility in some organic solvents (such as chloroform, dimethyl sulfoxide and dimethylformamide).
Use:
It has a wide range of applications:
-Drug research: It can be used as an intermediate for the synthesis of anti-cancer drugs, antiviral drugs and other biologically active molecules.
-Pesticide research: It can be used to synthesize pesticides and insecticides and other compounds.
-Organic synthesis: It can be used to synthesize amino acids, nucleotides and other organic compounds.
Preparation Method:
Preparation usually includes the following steps:
1. First, pyrimidine is reacted with ammonia and sodium hydroxide to obtain 2-aminopyrimidine.
2. Then, 2-aminopyrimidine reacts with hydrochloric acid to generate 4-chloro-2-aminopyrimidine.
3. Finally, 4-chloro-2-aminopyrimidine reacts with sodium iodide to obtain fluorite.
Safety Information:
-is an organic compound, and attention should be paid to its protective measures during operation and storage.
-It may be harmful to health, sensitizing and irritating, and direct contact with skin and eyes should be avoided.
-When using, ensure that it is operated in a well-ventilated environment.
-Waste disposal shall comply with relevant laws and regulations.
Nature:
-Appearance: It is a white to light yellow crystalline powder.
-Melting point: Its melting point is about 168-171 degrees Celsius.
-Solubility: It has good solubility in some organic solvents (such as chloroform, dimethyl sulfoxide and dimethylformamide).
Use:
It has a wide range of applications:
-Drug research: It can be used as an intermediate for the synthesis of anti-cancer drugs, antiviral drugs and other biologically active molecules.
-Pesticide research: It can be used to synthesize pesticides and insecticides and other compounds.
-Organic synthesis: It can be used to synthesize amino acids, nucleotides and other organic compounds.
Preparation Method:
Preparation usually includes the following steps:
1. First, pyrimidine is reacted with ammonia and sodium hydroxide to obtain 2-aminopyrimidine.
2. Then, 2-aminopyrimidine reacts with hydrochloric acid to generate 4-chloro-2-aminopyrimidine.
3. Finally, 4-chloro-2-aminopyrimidine reacts with sodium iodide to obtain fluorite.
Safety Information:
-is an organic compound, and attention should be paid to its protective measures during operation and storage.
-It may be harmful to health, sensitizing and irritating, and direct contact with skin and eyes should be avoided.
-When using, ensure that it is operated in a well-ventilated environment.
-Waste disposal shall comply with relevant laws and regulations.
Last Update：2024-04-09 21:01:54
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CAS: 63558-65-6
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QQ: 3008007409
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CAS: 63558-65-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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