Name | Solvent Green 7 |
Synonyms | HPTS PYRANINE CI 59040 11389green C.I. 59040 greenno.204 Solvent Green 7 SOLVENT GREEN 7 c.i.solventgreen7 HOMOVERATRONITRIL c.i.solventgreen9 D AND C GREEN NO 8 HPTS TRISODIUM SALT pyranineconcentrated C.I. Solvent Green 7 LABOTEST-BB LT00159917 VERAPAMIL INTERMEDIATES CYANOMETHYL-3,4-DIMETHOXYBENZENE 8-hydroxypyrene-1,3,6-trisulfonate 8-hydroxypyrene-1,3,6-trisulfonic acid trisodium1-hydroxy-3,6,8-pyrenetrisulfonate trisodium 8-hydroxypyrene-1,3,6-trisulfonate 8-hydroxypyrene-1,3,6-trisulfonicacidsodiumsalt 3,6-pyrenetrisulfonicacid,8-hydroxy-trisodiumsalt 1,3,6-Pyrenetrisulfonicacid,8-hydroxy-,trisodiumsalt 8-HYDROXY-1,3,6-PYRENETRISULFONIC ACID TRISODIUM SALT 8-HYDROXYPYRENE-1,3,6-TRISULFONIC ACID, TRISODIUM SALT |
CAS | 6358-69-6 |
EINECS | 228-783-6 |
InChI | InChI=1/C16H10O10S3/c17-11-5-12(27(18,19)20)8-3-4-10-14(29(24,25)26)6-13(28(21,22)23)9-2-1-7(11)15(8)16(9)10/h1-6,17H,(H,18,19,20)(H,21,22,23)(H,24,25,26)/p-3 |
Molecular Formula | C16H7Na3O10S3 |
Molar Mass | 524.39 |
Density | 2.15 |
Melting Point | 62-63.5°C(lit.) |
Boling Point | 171-178°C10mm Hg(lit.) |
Flash Point | 250 °C |
Water Solubility | 300 g/L (25 ºC) |
Solubility | methanol: 0.1g/mL, clear |
Vapor Presure | 0Pa at 25℃ |
Appearance | Powder |
Color | yellow |
Maximum wavelength(λmax) | ['403 nm (Buffer pH 4.0); 454 nm\n(Buffer pH 9.0)'] |
Merck | 7954 |
BRN | 4107272 |
pKa | 7.3, (at 22℃) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
MDL | MFCD00037575 |
Use | Mainly used for paint, plastic products and other coloring |
In vitro study | Pyranine is capable of discriminating ranges of cations from the Cu + ion, even in competing environment. Pyranine displays a rapid fluorescence response (t 1/2 =1.66 min) towards the Cu + ion, and the micromolar detection limit enables the detection of the ion in environmental samples. The observed stoichiometry of complexation between Pyranine and Cu + is 2:1. The pH-sensitive fluorescent indicator Pyranine is studied to determine its usefulness as probes for the living cornea and anterior chamber. Adequate concentrations are reached in the cornea and anterior chamber after topical administration; measurements can be made by fluorophotometry for many hours. The pH is calculated by measuring the ratio of fluorescent intensity at two excitation wavelengths, I463/I404, a measurement which is dependent on pH but independent of the concentration of the fluorophore and other variables which can alter the intensity. In the rabbit eye, Pyranine in the cornea and anterior chamber is observed to undergo easily measurable changes in fluorescent ratios associated with lid closure and contact lens wear, indicating its sensitivity to mild changes in pH. |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S36/37 - Wear suitable protective clothing and gloves. S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
RTECS | UR2700000 |
TSCA | Yes |
HS Code | 29089990 |
Color index | 59040 |
Main application | Adhesives; agrochemicals; ammonia sensor; carbon dioxidesensor; oxygen sensor; measuring the size; color filters; Chemiluminant materials; Electrophoticdisplay (EPD) film materials; electroluminescentdisplays/materials; fuel cell; lasers;liquid crystal displays; luminescent materials;nanoparticles; papers; photoresist processes;photonic ionic liquids; soils; solar cell;sol-gel materials/processes/thin films;sonophotoluminescence; water tracers;evaluating liquid water flow in wood duringdrying |
Biological applications | ; hygiene products/soaps; food products;controlled-release system for proteins; Drug delivery; in opthalmology/retinal surgery; as a substrate for measuring exercise (AChE) activity, carbonic anatomy activity,esterases activity, β-glucuronic activity, lipaseactivity, sucrose phosphorylase (SPO)activity, phosphoglucomutase (PGM) activity;treating cancer, infection, immune/autoimmunedisease, mastitis, tonsillitis, tuberculosis|
LogP | -3.97 at 25℃ |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Application | solvent Green 7 is used as a fluorescent pH indicator with emission changes in the physiological pH range. It acts as a dye in optical sensor applications. It can be used as a colorant and a biological stain. It is also used to measure the pH of intracellular fluid within cells. |
biological activity | Pyranine (HPTS; Solvent Green 7) is a pH-sensitive fluorescent indicator. Pyranine is a class of fluorescent chemical sensors for Cu ions (λex = 450 nm,λem = 510 nm). |
Application | mainly used for coloring |