6381-92-6
EDTA disodium salt dihydrate
CAS: 6381-92-6
Molecular Formula: C10H14N2Na2O8· 2H2O
6381-92-6 - Names and Identifiers
6381-92-6 - Physico-chemical Properties
| Molecular Formula | C10H14N2Na2O8· 2H2O |
| Molar Mass | 372.24 |
| Melting Point | 252℃ |
| Water Solubility | soluble |
| Appearance | White crystal |
| Storage Condition | 2-8℃ |
| Sensitive | Easily absorbing moisture |
| MDL | MFCD00150037 |
| Physical and Chemical Properties | White crystalline powder. |
| Use | Used as a complexing agent, also used in the pharmaceutical industry, color development |
6381-92-6 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/38 - Irritating to eyes and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
6381-92-6 - Upstream Downstream Industry
| Raw Materials | Hydrochloric acid Chloroacetic acid Ethylenediamine Ethylenediaminetetraacetic acid |
| Downstream Products | Ethylenediaminetetraacetic acid tetrasodium salt |
6381-92-6 - Reference
| Reference Show more | 1. Yang Jingpeng, Song Yunbo, Li June, et al. Selenium-enriching ability of lactic acid bacteria and evaluation of its biological activity in vitro [J]. Chinese Journal of Food Science, 2019 019(001):171-182. 2. Song Xiu-Jie, Zhang Lei, Ju Hong-Mei, etc. Mutant prevention concentration of levofloxacin alone and combined with fosfomycin against Staphylococcus aureus [J]. Chinese Journal of Clinical Pharmacology, 2010, 26(12):888-892. 3. He Junhua, Marley Jing, Zhou Huiling. Effects of phlorizin on Botrytis cinerea of postharvest Apple [J]. Food Science, 2018, 039(015):190-196. 4. Ji Shujuan, Dong Ling, Zhou Xin, Li Rui, Cheng Shunchang. Effect of salicylic acid on ester aroma of Nanguo pear treated with 1-MCP during cold storage and its mechanism [J]. Chinese Journal of Food Science, 2016,16(06):167-173. 5. You bin, Huang Xiu-Zhu, Lin Yu, Huang Han. Changes of bone tissue morphology, bone mineral density and bone metabolism indexes in different parts of natural aging rats [J]. Chinese Journal of Tissue Engineering Research, 2021,25(26):4118-4122. 6. Yan, Congcong, et al. "Improved photoremoval performance of boron carbon nitride-pyromellitic dihydrogen composite by itself to change the solution pH." New Journal of Chemistry 44.26 (2020): 11105-11124.https://doi.org/10. 7. [IF=10.588] Yong Guo et al."UV-light promoted formation of boron nitride-fullerene composite and its photodegradation performance for antibiotics under visible light irradiation."J Hazard Mater. 2021 May;410:124628 8. [IF=4.539] Xinpeng Duan et al."Superhydrophobic and antibacterial wood enabled by polydopamine-assisted decoration of copper nanoparticles."Colloid Surface A. 2020 Oct;602:125145 9. [IF=3.591] Congcong Yan et al."Improved photoremoval performance of boron carbon nitride-pyromellitic dianhydride composite toward tetracycline and Cr(VI) by itself to change the solution pH."New J Chem. 2020 Jul;44(26):11105-11124 10. [IF=6.475] Tao-Tao Xue et al."Evaluation of antioxidant enzyme inhibition, nitric oxide production inhibitory activities and chemical profiles of the active extracts from the medicinal and edible plant: Althaea officinalis."Food Res Int. 2022 Jun;156:111166 11. [IF=7.267] Xianxian Lin et al."In-situ copper ion reduction and micro encapsulation of wood-based composite PCM with effective anisotropic thermal conductivity and energy storage."SOLAR ENERGY MATERIALS AND SOLAR CELLS. 2022 Aug;242:111762 12. [IF=3.605] Liu Kexin et al."Low-concentration iron promotes Klebsiella pneumoniae biofilm formation by suppressing succinic acid."BMC MICROBIOLOGY. 2022 Dec;22(1):1-10 |
6381-92-6 - Nature
Open Data Verified Data
white crystalline powder. Soluble in water, acidic solution. Slightly soluble in alcohol. mp252 C (decomposition); PH value of about 5.3. Toxic and corrosive flue gas is generated by high thermal decomposition.
Last Update：2024-01-02 23:10:35
6381-92-6 - Preparation Method
Open Data Verified Data
ethylenediaminetetraacetic acid and water were added to the enamel reaction tank, and sodium hydroxide solution was added with stirring. The reaction mixture was heated to complete reaction, and hydrochloric acid was added to pH 4.5. It is concentrated by heating to 90 ° C., filtered, the filtrate is cooled, the crystals are filtered off, washed with water, and dried at 70 ° C. To obtain disodium ethylenediaminetetraacetic acid.
Last Update：2022-01-01 09:25:20
6381-92-6 - Use
Open Data Verified Data
test for calcium, magnesium, etc. Used in pharmaceutical industry, color development, rare metal smelting and other fields. Is an important complexing agent and metal masking agent.
Last Update：2022-01-01 09:25:21
6381-92-6 - Safety
Open Data Verified Data
rat oral LD50:2000mg/kg. Store in a cool, ventilated warehouse. Keep away from fire and heat source. Protection from direct sunlight. Keep the container sealed. Should be stored separately from the oxidant, acid, alkali.
Last Update：2022-01-01 09:25:21
6381-92-6 - Introduction
Properties: EDTA disodium salt dihydrate is a white crystalline powder with good solubility in water. It exhibits excellent chelating properties and can form stable complexes with metal ions.
Uses: It is mainly used as a chelating agent and finds wide applications in chemical analysis, biochemistry, pharmaceuticals, etc. It is used in chelating filter paper, metal ion analysis, cell culture, pharmaceutical formulations, food additives, and more.
Synthesis: EDTA disodium salt dihydrate is typically prepared by reacting EDTA acid (ethylenediaminetetraacetic acid) with sodium hydroxide to form EDTA disodium salt, followed by crystallization and dehydration to obtain the dihydrate form.
Safety: EDTA disodium salt dihydrate is generally considered safe for most applications when used properly. However, it should be handled carefully and not mixed with strong oxidizers or acids to avoid adverse reactions. In cases of prolonged exposure or ingestion in large quantities, it may cause irritation to the eyes, skin, or gastrointestinal tract. Proper personal protective equipment should be worn when handling this compound.
Last Update：2024-04-09 20:49:11
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Raw Materials for 6381-92-6
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