6480-68-8
3-Quinolinecarboxylic acid
CAS: 6480-68-8
Molecular Formula: C10H7NO2
6480-68-8 - Names and Identifiers
| Name | 3-Quinolinecarboxylic acid |
| Synonyms | AKOS BBS-00005333 3-Carboxyquinoline. RARECHEM AL BO 1256 quinoline-3-carboxylate 3-Quinolinecarboxylic acid 3-QUINOLINECARBOXYLIC ACID QUINOLINE-3-CARBOXYLIC ACID Quinoline-3-carboxylic acid |
| CAS | 6480-68-8 |
| EINECS | 229-337-3 |
| InChI | InChI=1/C10H7NO2/c12-10(13)8-5-7-3-1-2-4-9(7)11-6-8/h1-6H,(H,12,13)/p-1 |
| InChIKey | DJXNJVFEFSWHLY-UHFFFAOYSA-N |
6480-68-8 - Physico-chemical Properties
| Molecular Formula | C10H7NO2 |
| Molar Mass | 173.17 |
| Density | 1.2427 (rough estimate) |
| Melting Point | 277-280 °C (lit.) |
| Boling Point | 303.81°C (rough estimate) |
| Flash Point | 164.7°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 1.85E-05mmHg at 25°C |
| Appearance | Powder |
| Color | White to slightly beige |
| BRN | 126542 |
| pKa | 2.20±0.30(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.5200 (estimate) |
| MDL | MFCD00006770 |
6480-68-8 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R36/38 - Irritating to eyes and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37 - Wear suitable gloves. |
| WGK Germany | 3 |
| HS Code | 29334900 |
6480-68-8 - Introduction
3-Quinolinecarboxylic acid(3-Quinolinecarboxylic acid) is an organic compound with the chemical formula C10H7NO2. It is a white solid, stable at room temperature and pressure. The following is an introduction to some properties, uses, preparation methods and safety information about 3-Quinolinecarboxylic acid:
Nature:
-Appearance: White solid with visible crystals
-Solubility: Low solubility in water, soluble in organic solvents such as ethanol, dimethylformamide, etc.
-Melting point: about 283 ℃
-Molecular weight: about 173.17g/mol
Use:
- 3-Quinolinecarboxylic acid is an important organic intermediate, which is widely used in the fields of drug synthesis, pesticide synthesis and dye synthesis.
-In the field of medicine, 3-Quinolinecarboxylic acid can be used to synthesize some biologically active compounds, such as anti-tumor drugs, anti-infective drugs, etc.
-In the field of pesticides, 3-Quinolinecarboxylic acid can be used to synthesize some fungicides and insecticides.
-In the field of dye synthesis, 3-Quinolinecarboxylic acid can be used to synthesize some organic light-emitting materials and photosensitive materials.
Preparation Method:
- 3-Quinolinecarboxylic acid has a variety of synthesis methods, common methods include:
-Using quinoline as the starting material, quinoline-N-oxide is obtained by oxidation reaction, and then 3-Quinolinecarboxylic acid is obtained by acid treatment.
-2-chloroquinoline reacts with alkaline sodium hydroxide to generate quinoline 2-carboxyacetic acid, which is then treated with acid to obtain 3-quinolinecarboxylic acid.
Safety Information:
- 3-Quinolinecarboxylic acid does not have obvious safety risks under normal conditions of use.
-As a chemical, care should be taken to avoid contact with skin and inhalation of dust. If contact occurs, rinse immediately with plenty of water and seek medical help.
-Compliance with safe handling and storage practices for chemicals during use and storage.
Nature:
-Appearance: White solid with visible crystals
-Solubility: Low solubility in water, soluble in organic solvents such as ethanol, dimethylformamide, etc.
-Melting point: about 283 ℃
-Molecular weight: about 173.17g/mol
Use:
- 3-Quinolinecarboxylic acid is an important organic intermediate, which is widely used in the fields of drug synthesis, pesticide synthesis and dye synthesis.
-In the field of medicine, 3-Quinolinecarboxylic acid can be used to synthesize some biologically active compounds, such as anti-tumor drugs, anti-infective drugs, etc.
-In the field of pesticides, 3-Quinolinecarboxylic acid can be used to synthesize some fungicides and insecticides.
-In the field of dye synthesis, 3-Quinolinecarboxylic acid can be used to synthesize some organic light-emitting materials and photosensitive materials.
Preparation Method:
- 3-Quinolinecarboxylic acid has a variety of synthesis methods, common methods include:
-Using quinoline as the starting material, quinoline-N-oxide is obtained by oxidation reaction, and then 3-Quinolinecarboxylic acid is obtained by acid treatment.
-2-chloroquinoline reacts with alkaline sodium hydroxide to generate quinoline 2-carboxyacetic acid, which is then treated with acid to obtain 3-quinolinecarboxylic acid.
Safety Information:
- 3-Quinolinecarboxylic acid does not have obvious safety risks under normal conditions of use.
-As a chemical, care should be taken to avoid contact with skin and inhalation of dust. If contact occurs, rinse immediately with plenty of water and seek medical help.
-Compliance with safe handling and storage practices for chemicals during use and storage.
Last Update：2024-04-09 15:17:59
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Product Name: 3-Quinolinecarboxylic acid Visit Supplier Webpage Request for quotationCAS: 6480-68-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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