65-71-4
Thymine
CAS: 65-71-4
Molecular Formula: C5H6N2O2
65-71-4 - Names and Identifiers
| Name | Thymine |
| Synonyms | Thy THYMIN Thymine THYMINE 5-Methyluracil 5-methyl-uracil 5-methyl uracil thymin(purinebase) LABOTEST-BB LT00848102 5-methylpyrimidine-2,4-diol 5-Methyl-2,4-dioxypyrimidine 5-Methylpyrimidine-2,4-dione 2,4-dioxy-5-methyl pyrimidine 2,4-Dihydroxy-5-methylpyrimidine 5-Methyl-2,4(1H,3H)-pyrimidinedione 5-methylpyrimidine-2,4(1H,3H)-dione 4(1H,3H)-Pyrimidinedione,5-methyl-2 2,4(1H,3H)-Pyrimidinedione, 5-methyl- Thymine 2-4-Dihydroxy-5-methylpyrimidine |
| CAS | 65-71-4 |
| EINECS | 200-616-1 |
| InChI | InChI=1/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9) |
| InChIKey | RWQNBRDOKXIBIV-UHFFFAOYSA-N |
65-71-4 - Physico-chemical Properties
| Molecular Formula | C5H6N2O2 |
| Molar Mass | 126.11 |
| Density | 1.3541 (rough estimate) |
| Melting Point | ~320 °C (dec.) (lit.) |
| Boling Point | 234.21°C (rough estimate) |
| Flash Point | 198°C |
| Water Solubility | Soluble in hot water. Slightly soluble in alcohol. |
| Solubility | Insoluble in water at room temperature, slightly soluble in alcohol, soluble in lye, acid, formamide, DMF and pyridine |
| Vapor Presure | 4.25E-07mmHg at 25°C |
| Appearance | White crystalline powder |
| Color | White |
| Merck | 14,9398 |
| BRN | 607626 |
| pKa | 9.94(at 25℃) |
| Storage Condition | Sealed in dry,Room Temperature |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Sensitive | Sensitive to light |
| Refractive Index | 1.5090 (estimate) |
| MDL | MFCD00006026 |
| Physical and Chemical Properties | Melting point 316-317°C |
| Use | Is a key intermediate for the synthesis of anti-AIDS drugs AZT, DDT and related drugs |
65-71-4 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36 - Irritating to the eyes R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 2 |
| RTECS | XP2100000 |
| TSCA | Yes |
| HS Code | 29335990 |
65-71-4 - Upstream Downstream Industry
| Raw Materials | Acetic acid n-Butyl acetate Methyl alcohol Methyl methacrylate Urea Hydrochloric acid Ethyl Alcohol |
65-71-4 - Reference
| Reference Show more | 1. Wang Huimin, Feng Xuesong. Separation of graphene oxide/Cationic Cellulose composites by capillary electrophoresis [J]. Analytical Laboratory, 2015, 34(012):1395-1398. 2. Zhang Lei, Wang Yanhua, Liu Chang, etc. Analysis and Evaluation of chemical quality of donkey skin glue and deer skin glue [J]. Food Science, 2018, 039(022):57-63. 3. Feng hygienic, Li Fang, Guo menghuan, et al. A new pyrazine derivative from Dioscorea opposita [J]. Chinese Journal of Pharmacy, 2017(08):101-103. 4. Gao Kun, Gong, Rui Ze, Li Shanshan, et al. Simultaneous determination of 13 nucleosides in ginseng by UPLC [J]. Food Industry 2019. 5. On behalf of Lily, Jin Shanxia, fan Mengying, etc. Application of quaternized β-cyclodextrin grafted chitosan coating in capillary electrophoresis separation [J]. Analytical Laboratory, 2017, 08(v.36):15-18. 6. Ma, Ke, et al. "A sensitive and selective “turn-on” fluorescent probe for Hg 2 based on thymine-Hg 2 -thymine complex with an aggregation-induced emission feature." Analytical Methods 6.7 (2014): 2338-2342. 7. Zhen Yang, Mingji Li, Hongji Li, Huayi Li, Cuiping Li, Baohe Yang, Polycrystalline boron-doped diamond-based electrochemical biosensor for simultaneous detection of dopamine and melatonin Analytica Chimica Acta, Volume 1135, 2020, Pages 73-82, ISSN 0003-2 8. Huang, Dihui, et al. "Determination of global DNA methylation level by capillary electrophoresis using octyl-modified quaternized cellulose as an electrolyte additive." Analytical and bioanalytical chemistry 406.12 (2014): 2771-2777.https://doi.org/10.1007 9. Song, G., Zhang, R., Jiang X. et al. Nitrogen-doped reduced graphene oxide as a sensing platform for detection of guanine and application in cell necrosis. Chem. Pap. 74, 89-98 (2020). https://doi.org/10.1007/s11696-019-00856-0 10. Hengqiang Zhao, Changjiangsheng Lai, Minmin Zhang, Siduo Zhou, Qian Liu, Daijie Wang, Yanling Geng Xiao Wang,An improved 2D-HPLC-UF-ESI-TOF/MS approach for enrichment and comprehensive characterization of minor neuraminidase inhibitors from Flos Lonicera 11. Hengqiang Zhao, Changjiangsheng Lai, Minmin Zhang, Siduo Zhou, Qian Liu, Daijie Wang, Yanling Geng, Xiao Wang,An improved 2D-HPLC-UF-ESI-TOF/MS approach for enrichment and comprehensive characterization of minor neuraminidase inhibitors from Flos Lonicera 12. [IF=6.558] Zhen Yang et al."Polycrystalline boron-doped diamond-based electrochemical biosensor for simultaneous detection of dopamine and melatonin."Anal Chim Acta. 2020 Oct;1135:73 13. [IF=4.464] Junqing Qin et al."Growth of monolayer and multilayer graphene on glassy carbon electrode for simultaneous determination of guanine, adenine, thymine, and cytosine."J Electroanal Chem. 2021 Aug;895:115403 14. [IF=3.935] Hengqiang Zhao et al."An improved 2D-HPLC-UF-ESI-TOF/MS approach for enrichment and comprehensive characterization of minor neuraminidase inhibitors from Flos Lonicerae Japonicae."J Pharmaceut Biomed. 2019 Oct;175:112758 15. [IF=6.558] Tianrun Zhang et al."Molecularly imprinted Ni-polyacrylamide-based electrochemical sensor for the simultaneous detection of dopamine and adenine."Anal Chim Acta. 2022 Apr;1202:339689 16. [IF=6.529] Yarigui Bao et al."Therapeutic effects of Chinese medicine Di-Long (Pheretima vulgaris) on rheumatoid arthritis through inhibiting NF-κB activation and regulating Th1/Th2 balance."Biomed Pharmacother. 2022 Mar;147:112643 |
65-71-4 - Introduction
Easily soluble in lye and salt, soluble in acid, formamide, DMF and pyridine. Soluble in hot water, slightly soluble in cold water, ethanol, ether. Decomposition at 335~337 ℃.
Last Update：2022-10-16 17:27:44
Supplier List
Multiple SpecificationsSpot supply
Product Name: Thymine Request for quotationCAS: 65-71-45-
Tel: 15335994747
Email: 3521670276@qq.com
Mobile: 15335994747
QQ: 3521670276
Wechat: A2020071098
Spot supply
Product Name: Thymine Request for quotationCAS: 65-71-4
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: Thymine Request for quotationCAS: 65-71-4
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Spot supply
Product Name: Stavudine Impurity 1 (Stavudine EP Impurity A) Visit Supplier Webpage Request for quotationCAS: 65-71-4
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: Thymine Request for quotation
CAS: 65-71-4
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 65-71-4
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Product Name: Thymine Request for quotation
CAS: 65-71-4
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 65-71-4
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Multiple SpecificationsSpot supply
Product Name: Thymine Visit Supplier Webpage Request for quotationCAS: 65-71-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: Thymine Request for quotation
CAS: 65-71-4
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987
Wechat: 13605431940
WhatsApp: 13605431940
CAS: 65-71-4
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987
Wechat: 13605431940
WhatsApp: 13605431940
Multiple SpecificationsSpot supply
Product Name: Thymine Request for quotationCAS: 65-71-45-
Tel: 15335994747
Email: 3521670276@qq.com
Mobile: 15335994747
QQ: 3521670276
Wechat: A2020071098
Spot supply
Product Name: Thymine Request for quotationCAS: 65-71-4
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: Thymine Request for quotationCAS: 65-71-4
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Spot supply
Product Name: Stavudine Impurity 1 (Stavudine EP Impurity A) Visit Supplier Webpage Request for quotationCAS: 65-71-4
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: Thymine Request for quotation
CAS: 65-71-4
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 65-71-4
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Product Name: Thymine Request for quotation
CAS: 65-71-4
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 65-71-4
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Multiple SpecificationsSpot supply
Product Name: Thymine Visit Supplier Webpage Request for quotationCAS: 65-71-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: Thymine Request for quotation
CAS: 65-71-4
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987
Wechat: 13605431940
WhatsApp: 13605431940
CAS: 65-71-4
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987
Wechat: 13605431940
WhatsApp: 13605431940
View History
Raw Materials for 65-71-4