654-47-7
2-氟苯基甲基砜
CAS: 654-47-7
Molecular Formula: C7H7FO2S
654-47-7 - Names and Identifiers
| Name | 2-氟苯基甲基砜 |
| Synonyms | 2-FLUOROPHENYLMETHYLSULFONE 2-Fluorophenyl phenyl sulfone 1-Fluoro-2-(methylsulphonyl)Benzene Benzene, 1-fluoro-2-(methylsulfonyl)- |
| CAS | 654-47-7 |
654-47-7 - Physico-chemical Properties
| Molecular Formula | C7H7FO2S |
| Molar Mass | 174.19 |
| Density | 0.975 |
| Melting Point | 48-52 °C |
| Boling Point | 304.5±34.0 °C(Predicted) |
| Flash Point | 110℃ |
| Storage Condition | Sealed in dry,Room Temperature |
654-47-7 - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
| Hazard Note | Irritant |
654-47-7 - Introduction
2-Fluorophenyl methyl sulfone is an organic compound with the chemical formula C7H7FO2S. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-fluorophenyl methyl sulfone is a colorless to slightly yellow liquid.
-Density: Its density is about 1.28g/cm³.
-Boiling point: The boiling point of 2-fluorophenyl methyl sulfone is about 230°C.
-Solubility: It has good solubility in organic solvents, such as ethanol, acetone and dimethylformamide.
Use:
-2-Fluorophenyl methyl sulfone is an important organic synthesis intermediate, which is widely used in the synthesis of pesticides, pharmaceuticals, dyes and chemicals.
-It can be used as a raw material for the synthesis of a variety of drugs and pesticides, such as clothianidin and thiamethoxam.
- 2-fluorophenyl methyl sulfone can also be used as a synthetic reagent for dyes and pigments.
-In addition, it can also be used as a catalyst, photopolymerization initiator and a ligand for photosensitizers.
Preparation Method:
The preparation method of-2-fluorophenyl methyl sulfone can be obtained by the reaction of phenol and chloroformic acid. The specific process involves the reaction of phenol with chloroformic acid to form 2-chlorophenylcarboxylic acid, which is then reacted with potassium fluoride to form 2-fluorophenylcarboxylic acid. Finally, 2-fluorophenylcarboxylic acid is converted to 2-fluorophenyl methyl sulfone using a sulfoxide reaction.
Safety Information:
-2-Fluorophenyl methyl sulfone is generally a relatively safe compound under normal use and storage conditions.
-Because it is an organic compound, pay attention to prevent contact with skin and eyes when using it to avoid irritation or damage. At the same time, to maintain good ventilation conditions, avoid inhalation of its vapor.
-Use in accordance with relevant safety practices, such as wearing appropriate personal protective equipment and working with chemicals. In case of accidental splashing on the skin or eyes, rinse with plenty of water and seek medical help in a timely manner.
Nature:
-Appearance: 2-fluorophenyl methyl sulfone is a colorless to slightly yellow liquid.
-Density: Its density is about 1.28g/cm³.
-Boiling point: The boiling point of 2-fluorophenyl methyl sulfone is about 230°C.
-Solubility: It has good solubility in organic solvents, such as ethanol, acetone and dimethylformamide.
Use:
-2-Fluorophenyl methyl sulfone is an important organic synthesis intermediate, which is widely used in the synthesis of pesticides, pharmaceuticals, dyes and chemicals.
-It can be used as a raw material for the synthesis of a variety of drugs and pesticides, such as clothianidin and thiamethoxam.
- 2-fluorophenyl methyl sulfone can also be used as a synthetic reagent for dyes and pigments.
-In addition, it can also be used as a catalyst, photopolymerization initiator and a ligand for photosensitizers.
Preparation Method:
The preparation method of-2-fluorophenyl methyl sulfone can be obtained by the reaction of phenol and chloroformic acid. The specific process involves the reaction of phenol with chloroformic acid to form 2-chlorophenylcarboxylic acid, which is then reacted with potassium fluoride to form 2-fluorophenylcarboxylic acid. Finally, 2-fluorophenylcarboxylic acid is converted to 2-fluorophenyl methyl sulfone using a sulfoxide reaction.
Safety Information:
-2-Fluorophenyl methyl sulfone is generally a relatively safe compound under normal use and storage conditions.
-Because it is an organic compound, pay attention to prevent contact with skin and eyes when using it to avoid irritation or damage. At the same time, to maintain good ventilation conditions, avoid inhalation of its vapor.
-Use in accordance with relevant safety practices, such as wearing appropriate personal protective equipment and working with chemicals. In case of accidental splashing on the skin or eyes, rinse with plenty of water and seek medical help in a timely manner.
Last Update：2024-04-09 21:11:58
