660406-84-8

660406-84-8 - Names and Identifiers

Name	1-Piperidinecarboxylic acid, 4-(cyanoacetyl)-, 1,1-dimethylethyl ester
Synonyms	1-BOC-4-(CYANOACETYL)PIPERIDINE 1-Boc-4-(2-cyanoacetyl)piperidine 4-(Cyanoacetyl)piperidine, N-BOC protected tert-Butyl 4-(2-cyanoacetyl)piperidine-1-carboxylate 4-(2-Cyanoacetyl)piperidine-1-carboxylic acid tert-butyl ester 1-Piperidinecarboxylic acid, 4-(cyanoacetyl)-, 1,1-diMethylethyl ester 1-Piperidinecarboxylic acid, 4-(cyanoacetyl)-, 1,1-dimethylethyl ester tert-Butyl 4-(cyanoacetyl)piperidine-1-carboxylate, 1-(tert-Butoxycarbonyl)-4-(cyanoacetyl)piperidine, 3-[1-(tert-Butoxycarbonyl)piperidin-4-yl]-3-oxopropanenitrile
CAS	660406-84-8

660406-84-8 - Physico-chemical Properties

Molecular Formula	C13H20N2O3
Molar Mass	252.31
Density	1.117±0.06 g/cm3(Predicted)
Boling Point	365.0±32.0 °C(Predicted)
pKa	9.36±0.20(Predicted)
Storage Condition	Inert atmosphere,Room Temperature

660406-84-8 - Introduction

1-Piperidinecarboxylic acid, 4-(cyanoacetyl)-, 1,1-dimethylethyyl ester is a compound whose chemical formula is C16H23N3O3. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: colorless liquid or solid (depending on its state)
-Molecular weight: 309.37g/mol
-Melting point: approx. 50°C-52°C
-Boiling point: about 375°C (decomposition)
-Solubility: More soluble in organic solvents, such as ethanol and ethers
-Stability: Stable at room temperature, but may decompose under high temperature or light

Use:
- 1-Piperidinecarboxylic acid, 4-(cyanoacetyl)-, 1,1-dimethylethyl ester is often used in organic synthesis as an important intermediate compound. It can be used to synthesize biologically active molecules, such as drugs, pesticides and dyes.

Preparation Method:
- 1-Piperidinecarboxylic acid, 4-(cyanoacetyl)-, 1,1-dimethylethyl ester can be synthesized by the following steps:
1) First, 1-piperidinecarboxylic acid is reacted with chloroacetyl chloride in the presence of a base to obtain chloroacetyl 1-piperidinecarboxylate.
2) Then, the obtained ester is reacted with tert-butyl alcohol under base catalysis to generate 1-Piperidinecarboxylic acid, 4-(cyanoacetyl)-, 1,1-dimethyl ester.

Safety Information:
- 1-Piperidinecarboxylic acid, 4-(cyanoacetyl)-, 1,1-dimethylethyl ester is an organic compound and should be processed in accordance with routine laboratory operations.
-Wear appropriate personal protective equipment such as lab gloves, goggles and lab coats when handling or operating.
-The compound has low toxicity but may be irritating to the eyes, skin and respiratory tract.
-During use and storage, keep away from open flames and high temperatures.
-When handling this compound, care should be taken to prevent inhalation of gas and contact with skin.
-If you accidentally come into contact with or ingestion of the compound, you should immediately consult a professional and provide all relevant information about the compound.

Please note that this is only a basic introduction to 1-Piperidinecarboxylic acid, 4-(cyanoacetyl)-, 1,1-dimethylethyl ester. If you need more detailed or specific information, please refer to the relevant chemical literature or consult a professional.

Last Update：2024-04-09 21:01:54