66286-21-3 - Names and Identifiers
Name | 2',3',4',5'-tetrafluoroacetophenone
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Synonyms | Tetrafluoroacetophenone 2',3',4',5'-Tertafluoroacetophenone 2',3',4',5'-TETRAFLUOROACETOPHENONE 2',3',4',5'-tetrafluoroacetophenone 1-(2,3,4,5-Tetrafluorophenyl)ethanone 1-(2,3,4,5-tetrafluorophenyl)ethanone Ethanone, 1-(2,3,4,5-tetrafluorophenyl)- 1-(2,3,4,5-Tetrafluorophenyl)ethan-1-one 1-(2,3,4,5-Tetrafluorophenyl)ethan-1-one, 1-Oxo-1-(2,3,4,5-tetrafluorophenyl)ethane
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CAS | 66286-21-3
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InChI | InChI=1/C8H4F4O/c1-3(13)4-2-5(9)7(11)8(12)6(4)10/h2H,1H3 |
66286-21-3 - Physico-chemical Properties
Molecular Formula | C8H4F4O
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Molar Mass | 192.11 |
Density | 1.408g/mLat 25°C(lit.) |
Boling Point | 83-84°C20mm Hg(lit.) |
Flash Point | 156°F |
Vapor Presure | 0.649mmHg at 25°C |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | n20/D 1.453(lit.) |
66286-21-3 - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S23 - Do not breathe vapour.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S28 - After contact with skin, wash immediately with plenty of soap-suds.
S36 - Wear suitable protective clothing.
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WGK Germany | 3 |
66286-21-3 - Introduction
2 ',3',4 ',5'-tetrafluoroacetophenone, formula C8H4F4O, molecular weight 184.11g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
1. Appearance: 2 ',3',4 ',5'-tetrafluoroacetophenone is a colorless liquid.
2. melting point:-26 ℃
3. Boiling point: 150-152 ℃
4. Density: 1.459g/cm3
5. Solubility: 2 ',3',4 ',5'-tetrafluoroacetophenone are soluble in many organic solvents, such as alcohols, ethers and aromatic hydrocarbons.
Use:
1. 2 ',3',4 ',5'-tetrafluoroacetophenone can be used as intermediates in organic synthesis for the synthesis of other compounds.
2. It can also be used as a solvent and catalyst in chemical reactions.
Preparation Method:
br> A method for synthesizing 2 ',3',4 ',5'-tetrafluoroacetophenone involves reacting 4 '-chloroacetophenone with aryl fluoride in the presence of a base, and then reacting with bromofluoroalkane in dichloromethane.
Safety Information:
1. 2 ',3',4 ',5'-tetrafluoroacetophenone may be irritating to eyes, skin and respiratory tract.
2. Avoid inhalation or contact with skin. If you do, rinse immediately with plenty of water. In case of eye contact, rinse immediately with plenty of water for at least 15 minutes and seek medical attention.
3. Avoid contact with fire and oxidant during storage.
4. lighting equipment should be safe and reliable when used to prevent fire and explosion.
5. 2 ',3',4 ',5'-tetrafluoroacetophenone are irritating chemicals. Please ensure good ventilation during use.
6. If accidental exposure or poisoning occurs, please seek medical attention and provide this article and product label to your doctor for reference.
Last Update:2024-04-10 22:29:15