663601-56-7
Benzene, 2-bromo-3,4-difluoro-1-(trifluoromethyl)-
CAS: 663601-56-7
Molecular Formula: C7H2BrF5
663601-56-7 - Names and Identifiers
663601-56-7 - Physico-chemical Properties
| Molecular Formula | C7H2BrF5 |
| Molar Mass | 260.99 |
663601-56-7 - Introduction
Benzene, 2-bromo-3,4-difluoro-1-(trifluoromethyl)-is an organic compound with the chemical formula C7H4BrF3 and a molecular weight of 219.01g/mol. It is a colorless liquid, soluble in organic solvents. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Melting point:-7 ℃
-Boiling point: 190-191 ℃
-Density: 1.773g/cm³
-Flash Point: 63 ℃
-Solubility: Soluble in organic solvents such as ether, acetone and chloroform.
Use:
- Benzene, 2-bromo-3,4-difluoro-1-(trifluoromethyl)-is widely used as an important intermediate in organic synthesis.
-It can be used in the synthesis of certain drugs, such as antiviral drugs.
-Due to its high affinity for fluorine, it can also be used as a source of fluorine content markers.
Preparation Method:
Benzene, the preparation method of 2-bromo-3,4-difluoro-1-(trifluoromethyl)-can be carried out by the following steps:
1. the reaction of benzene and brominated sulfoxide to obtain bromophenyl sulfone.
2. the compound reacts with CH2(CF3)2 under the catalysis of nickel hydride or other reducing agents to give Benzene, 2-bromo-3,4-difluoro-1-(trifluoromethyl)-.
Safety Information:
- Benzene, 2-bromo-3,4-difluoro-1-(trifluoromethyl)-irritating to skin and eyes, avoid direct contact.
-Wear appropriate protective equipment such as lab gloves and goggles when using.
-Avoid inhaling vapors and have good ventilation in the working environment.
-may produce toxic gases when burning, so keep away from open flames and high temperatures.
-Avoid contact with strong oxidants.
-Store away from fire and heat sources and keep the container tightly closed.
Nature:
-Appearance: colorless liquid
-Melting point:-7 ℃
-Boiling point: 190-191 ℃
-Density: 1.773g/cm³
-Flash Point: 63 ℃
-Solubility: Soluble in organic solvents such as ether, acetone and chloroform.
Use:
- Benzene, 2-bromo-3,4-difluoro-1-(trifluoromethyl)-is widely used as an important intermediate in organic synthesis.
-It can be used in the synthesis of certain drugs, such as antiviral drugs.
-Due to its high affinity for fluorine, it can also be used as a source of fluorine content markers.
Preparation Method:
Benzene, the preparation method of 2-bromo-3,4-difluoro-1-(trifluoromethyl)-can be carried out by the following steps:
1. the reaction of benzene and brominated sulfoxide to obtain bromophenyl sulfone.
2. the compound reacts with CH2(CF3)2 under the catalysis of nickel hydride or other reducing agents to give Benzene, 2-bromo-3,4-difluoro-1-(trifluoromethyl)-.
Safety Information:
- Benzene, 2-bromo-3,4-difluoro-1-(trifluoromethyl)-irritating to skin and eyes, avoid direct contact.
-Wear appropriate protective equipment such as lab gloves and goggles when using.
-Avoid inhaling vapors and have good ventilation in the working environment.
-may produce toxic gases when burning, so keep away from open flames and high temperatures.
-Avoid contact with strong oxidants.
-Store away from fire and heat sources and keep the container tightly closed.
Last Update：2024-04-09 21:04:16
