675-21-8 - Names and Identifiers
675-21-8 - Physico-chemical Properties
Molecular Formula | C4H3FN2
|
Molar Mass | 98.08 |
Density | 1.224±0.06 g/cm3(Predicted) |
Boling Point | 129.0±13.0 °C(Predicted) |
pKa | 1.62±0.10(Predicted) |
Storage Condition | 2-8°C |
675-21-8 - Risk and Safety
UN IDs | 1993 |
Hazard Class | IRRITANT |
Packing Group | Ⅲ |
675-21-8 - Introduction
5-Fluoropyrimidine, chemical formula is C4H3FN2, is a fluorine-containing pyrimidine compounds. The following is a description of some of the properties, uses, methods and safety information of 5-Fluoropyrimidine:
Nature:
-Appearance: 5-Fluoropyrimidine is a white to pale yellow crystalline solid.
-Solubility: It has poor solubility in water and can be dissolved in organic solvents such as ethanol and dimethyl sulfoxide.
-Stability: 5-Fluoropyrimidine is relatively stable at room temperature.
Use:
-Drug: 5-Fluoropyrimidine is an important raw material for anti-tumor drugs, which is widely used in the manufacture of anti-cancer drugs.
-Chemical research: 5-Fluoropyrimidine can be used to synthesize other pyrimidine compounds, such as the anticancer drug 5-fluorouracil.
Preparation Method:
The preparation method of-5-Fluoropyrimidine can be obtained by reacting pyrimidine with fluorine gas. The reaction process is generally carried out under light conditions, and a suitable catalyst is used to promote the reaction.
Safety Information:
- 5-Fluoropyrimidine is a toxic compound that needs to be handled and stored under appropriate laboratory conditions.
-When contacting 5-Fluoropyrimidine, avoid direct contact with skin and eyes, and pay attention to avoid inhaling its dust or steam.
-When disposing of 5-Fluoropyrimidine, it should be handled in accordance with the local regulations to prevent pollution to the environment.
Last Update:2024-04-09 02:00:47