6792-09-2
Mesaconine
CAS: 6792-09-2
Molecular Formula: C24H39NO9
6792-09-2 - Names and Identifiers
6792-09-2 - Physico-chemical Properties
| Molecular Formula | C24H39NO9 |
| Molar Mass | 485.57 |
| Density | 1.44±0.1 g/cm3(Predicted) |
| Boling Point | 617.1±55.0 °C(Predicted) |
| pKa | 12.22±0.70(Predicted) |
| Storage Condition | 室温 |
6792-09-2 - Reference Information
| background | aconite is a processed product of the seed root of Aconitum (AconitumcarmichaeliDebx.) of Ranunculaceae. It has the functions of returning to the yang to save the reverse, supplementing the fire to help the yang, chasing the wind, cold and dampness, warming the meridian and relieving pain. It is used for death yang collapse, limb cold pulse, impotence, uterine cold, heart and abdomen cold pain, deficiency cold vomiting and diarrhea, yin cold edema, yang deficiency external sensation, cold dampness arthralgia. |
| use | new use of neoaconitine in the preparation of drugs for the prevention and/or treatment of myocardial fibrosis and chronic heart failure caused by myocardial fibrosis |
| Pharmacological effects | 1) Inhibit or reverse myocardial tissue fibrosis; 2) Improve abnormal cardiac remodeling; 3) Improve cardiac dysfunction; 4) Improve chronic heart failure caused by myocardial fibrosis The survival rate of mice; 5) Against myocardial tissue inflammation; 6) Inhibit myocardial cell apoptosis; 7) Myocardial enzyme activity in dead mice, its mechanism of action is related to inhibiting myocardial inflammation and fibrosis caused by adriamycin and resisting myocardial cell apoptosis. |
| biological activity | Mesaconinean is an active ingredient extracted from Aconitum carmichaelii Debx., which has an effect on cardiovascular system. |
Last Update：2024-04-09 21:04:16
