Name | Sodium danshensu |
Synonyms | Sodium danshensu DANSHENSU SODIUM (RG) Salvia natriuretic peptide Sodium 3-(3,4-dihydroxyphenyl)lactate Sodium DL-beta-(3,4-dihydroxyphenyl)lactate 3-(3',4'-Dihydroxyphenyl)lactic acid sodium salt 3-(3',4'-Dihydroxyphenyl)lactic acid sodium salt 3,4-Dihydroxyphenyl-α-hydroxypropanoic acid sodium salt 3,4-Dihydroxyphenyl-.alpha.-hydroxypropanoic acid sodiuM salt |
CAS | 67920-52-9 |
EINECS | 804-287-0 |
Molecular Formula | C9H11NaO5 |
Molar Mass | 222.17 |
Melting Point | 255~258°C |
Solubility | Soluble in methanol and water, insoluble in chloroform and ether. |
Appearance | White needle crystal |
Storage Condition | Inert atmosphere,2-8°C |
MDL | MFCD09037393 |
Physical and Chemical Properties | Soluble in methanol, water, insoluble in chloroform, ether. It is derived from the root of the Labiatae plant Salvia miltiorrhiza Salvia miltiorrhiza miltiorrhiza Bge. And Salvia miltiorrhiza. |
Hazard Symbols | Xn - Harmful |
Risk Codes | 22 - Harmful if swallowed |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
HS Code | 29329990 |
Reference Show more | 1. Guanmin Guo Zhang Yuyan Wanhai the same. Effects of effective components of Salvia miltiorrhiza and Ligusticum Chuanxiong on brain endothelial cells in rats with hypoxic injury [J]. Journal of Anhui University of Traditional Chinese Medicine, 2014, 33(002):74-78. 2. Xia yunqiong. Study on validation of cleaning verification test method for danshen dripping injection [J]. Anhui medicine 2014 18(09):1650-1653. 3. Chen Juan, Deng Jun, Zhang Yuyan, et al. Regulatory mechanism of danshensu on lipid metabolism in hyperlipidemic rats [J]. Chinese Journal of Traditional Chinese Medicine, 2015, 40(2):313. 4. Zhang, qiongzhi, Shen, Cuizhen. Effect of sodium danshensu on pathology of compression site in rats with stage 2 pressure injury [J]. Zhejiang Journal of Traditional Chinese Medicine, 2019, 54(04):70-71. 5. Song Jizheng, Li Lingjun, Sun Peng, et al. Mechanism of bidirectional regulation of tyrosinase by total Salvianolic acid and separation of Salvianolic acid B by macroporous resin [J]. Central South Pharmacy 2016(4):402-406. 6. AI Jinchao He Yi, Yang Rongbing, etc. Pharmacokinetics of main active components of Danhong injection in rats with cerebral ischemia [J]. Chinese herbal medicine 2015 46(20):79-84. 7. Hu Weihui, Han Dong, Qijiang Kun, et al. Simultaneous determination of 12 components in Salvia przewalskii by RP-HPLC [J]. Journal of Pharmaceutical Analysis 2016 v.36(03):486-493. 8. Cheng Pei, Han Dongqi, Hu Weihui, etc. Simultaneous determination of 10 water-soluble and 4 fat-soluble components in Salvia miltiorrhiza by high performance liquid chromatography [J]. Journal of Pharmaceutical analysis, 2015(06):991-996. 9. Ma Dong-Lai Liu Ai-Peng-Lin Yue Xie Tao Liu Tao Zhu Feng-Li Chuli. Interaction between active components of Salvia miltiorrhiza and iron ions [J]. Guangzhou chemical industry, 2017, 45(14):117-118, 144. 10. Zheng Wen-hua, Yaya, cluster, et al. Quality Evaluation of wine Salvia miltiorrhiza standard decoction. Chinese Journal of Experimental prescriptions. 11. Li Cui, Wei Guangfei, Li Jia, etc. Study on the utilization value of Salvia miltiorrhiza with abnormal traits [J]. Shandong Science, 2014, 27(002):39-43. 12. Niumin Liu Hongyan Liu Qian et al. Correlation between the color and the contents of nine active components of Salvia miltiorrhiza for four cultivation years [J]. Chinese patent medicine 2017(1):131-135. 13. Wang Yun, Chen Junfeng, Zhang Lei, et al. Evaluation of quality of Salvia miltiorrhiza Bunge based on association analysis of "active components-traits" [J]. World Science and Technology: modernization of traditional Chinese medicine, 2019(5):835-843. 14. Cui Weiliang. Comparison of the distribution of chromatographic peaks of HPLC fingerprint before and after the processing of Danshen wine [J]. Liaoning Journal of Traditional Chinese Medicine, v.46;No.507(08):1707-1709. 15. Le Shijun, Wang Wenxiao, Gao Huan, Ren jionguo, Fu Ruijia, Li Jiajia, Chen Yanyu, Tang Yuping. Simultaneous determination of multiple active components in Danqi tablets from different manufacturers by HPLC [J]. Journal of Pharmaceutical Analysis, 2020,40(12):2236-2243. 16. Zhang, Xianhua, et al. "Danshen-Chuanxiong-Honghua ameliorates cerebral impairment and improves spatial cognitive deficits after transient focal ischemia and identification of active compounds." Frontiers in pharmacology 8 (2017): 452. 17. Zhang, Xianhua, et al. "Danshen-Chuanxiong-Honghua ameliorates cerebral impairment and improves spatial cognitive deficits after transient focal ischemia and identification of active compounds." Frontiers in pharmacology 8 (2017): 452. 18. [IF=3.645] Yang Wang et al."Identification of Salvia species using high-performance liquid chromatography combined with chemical pattern recognition analysis."J Sep Sci. 2018 Feb;41(3):609-617 19. [IF=5.455] Wang Qingjun et al."Fingerprint analysis of phenolic acid extract of Salvia miltiorrhiza by digital reference standard analyzer with one or two reference standards."Chin Med-Uk. 2021 Dec;16(1):1-16 20. [IF=3.411] Liu Hongyan et al."Effect Study of Continuous Monoculture on the Quality of Salvia miltiorrhiza Bge Roots."Biomed Res Int. 2020;2020:4284385 21. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950 |