68507-19-7

68507-19-7 - Names and Identifiers

Name	3-Iodo-4-methoxybenzoic acid
Synonyms	3-Iodo-4-methoxybenzoic acid 3-IODO-4-METHOXYBENZOIC ACID 3-Lodo-4-Methoxybenzoic acid Benzoic acid, 3-iodo-4-methoxy-
CAS	68507-19-7
InChI	InChI=1/C8H7IO3/c1-12-7-3-2-5(8(10)11)4-6(7)9/h2-4H,1H3,(H,10,11)

68507-19-7 - Physico-chemical Properties

Molecular Formula	C8H7IO3
Molar Mass	278.04
Density	1.878±0.06 g/cm3(Predicted)
Melting Point	239-243 °C
Boling Point	359.9±32.0 °C(Predicted)
Flash Point	171.5°C
Vapor Presure	8.3E-06mmHg at 25°C
pKa	4.12±0.10(Predicted)
Storage Condition	2-8°C
Sensitive	Light Sensitive
Refractive Index	1.631
MDL	MFCD00017347

68507-19-7 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37 - Wear suitable gloves.
WGK Germany	nwg
HS Code	29189900
Hazard Class	IRRITANT

68507-19-7 - Introduction

3-lodo-4-methoxybenzoic acid is an organic compound with the chemical formula C8H7IO3. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: 3-Iodo-4-methoxybenzic acid is a white crystalline solid.
-Melting point: about 180-182 degrees Celsius.
-Solubility: It has better solubility in some organic solvents (such as ethanol and dimethyl sulfoxide), but it has poor solubility in water.

Use:
3-lodo-4-methoxybenzoic acid is commonly used as an intermediate in organic synthesis and can be used to synthesize other organic compounds, such as drugs and pesticides.

Preparation Method:
3-Iodo-4-methoxy benzoic acid can be synthesized by the following steps:
1. 4-methoxybenzoic acid and iodine are reacted by sulfonic acid chloride to obtain 3-Iodo-4-methoxybenzoic acid sulfonate.
2. 3-Iodo-4-methoxybenzoic acid sulfonate is reacted with a base to generate 3-Iodo-4-methoxybenzoic acid.
3. Further purification and crystallization to obtain pure product.

Safety Information:
3-Iodo-4-methoxybenzoic acid has low toxicity, but the following safety precautions should be paid attention:
-Use with appropriate personal protective equipment, such as lab gloves and goggles.
-Avoid inhaling dust or contact with skin and eyes.
-If inhaled or exposed, rinse immediately with water and seek medical help.
-Stay away from ignition sources and combustible substances during operation.

Please note that the above information is for reference only. Please refer to the relevant chemical literature and laboratory guidelines for specific use, and follow the appropriate safety procedures.

Last Update：2024-04-09 15:17:59