68528-80-3

Name	Disuccinimidyl subera
Synonyms	DSS DSS Crosslinker Disuccinimidyl subera DISUCCINIMIDYL SUBERATE Di(N-succinimidyl) Suberate DISUCCINIMIDYL OCTANEDIOATE Bis-(N-succinimidyl)-suberate n-hydroxysuccinimidesubericacidester SUBERIC ACID BIS(N-HYDROXY-SUCCINIMIDE ESTER)
CAS	68528-80-3
EINECS	614-576-1
InChIKey	ZWIBGKZDAWNIFC-UHFFFAOYSA-N

Molecular Formula	C16H20N2O8
Molar Mass	368.34
Density	1.295 g/cm3
Melting Point	169-170°C
Boling Point	513.5±60.0 °C(Predicted)
Water Solubility	Insoluble in water. Soluble in chloroform: 50 mg/mL.
Solubility	chloroform: 50mg/mL
Appearance	powder
Color	White to Almost white
Storage Condition	2-8°C
In vitro study	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29171900

biological activity	DSS Crosslinker (disccinidiyl suberate) is a kind of cross-linking agent with the same and dual function, it is also a non-cleavable ADC linker and can be used for the synthesis of antibody-drug conjugate drugs (ADCs).
Use	a homologous bifunctional crosslinker with amine reactivity. The linkage to the primary amine-containing molecule is typically via an amide bond buffered to pH 6.5 (8.5-). A linker containing 8 atoms.

Last Update：2024-04-10 22:29:15

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68528-80-3

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