68813-55-8
OXANTEL PAMOATE
CAS: 68813-55-8
Molecular Formula: C49H48N4O8
68813-55-8 - Names and Identifiers
| Name | OXANTEL PAMOATE |
| Synonyms | OXANTEL PAMOATE 1-methyl-2-(3-hydroxyphenylethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4'-methylenebis(3-hydroxy-2-naphthoic acid) |
| CAS | 68813-55-8 |
| EINECS | 272-332-6 |
| InChIKey | WSYDAPQDBDVYIO-QEFJDTIGSA-N |
68813-55-8 - Physico-chemical Properties
| Molecular Formula | C49H48N4O8 |
| Molar Mass | 820.93 |
| Melting Point | >224°C (dec.) |
| Appearance | Shape neat, color White to Off-White |
| Storage Condition | Amber Vial, Refrigerator, Under inert atmosphere |
| Physical and Chemical Properties | Bioactive Oxantel pamoate is a widely used insect repellent, effectively targeting Trichuris muris and hookworm. |
68813-55-8 - Risk and Safety
| WGK Germany | 3 |
68813-55-8 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.218 ml | 6.091 ml | 12.181 ml |
| 5 mM | 0.244 ml | 1.218 ml | 2.436 ml |
| 10 mM | 0.122 ml | 0.609 ml | 1.218 ml |
| 5 mM | 0.024 ml | 0.122 ml | 0.244 ml |
Last Update：2024-01-02 23:10:35
68813-55-8 - Nature
| Solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated) |
Last Update：2024-04-10 22:29:15
68813-55-8 - Uses and synthesis methods
Target
Antiparasitic
In vivo studies
The activity of the veterinary drug Oxantel pamoate is studied against Trichuris muris , Ancylostoma ceylanicum and Necator americanus . An ED 50 s of 4.7 mg/kg is calculated for Oxantel pamoate against T. muris in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI)=2.53). Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED 50 s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to T. muris -infected mice. Oxantel pamoate (10 mg/kg) lacks activity against Ancylostoma ceylanicum and Necator americanus .
Last Update：2024-04-10 22:29:15
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Product Name: OXANTEL PAMOATE Visit Supplier Webpage Request for quotationCAS: 68813-55-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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