690632-14-5
tert-butyl4-(2-aminophenoxy)piperidine-1-carboxylate
CAS: 690632-14-5
Molecular Formula: C16H24N2O3
690632-14-5 - Names and Identifiers
| Name | tert-butyl4-(2-aminophenoxy)piperidine-1-carboxylate |
| Synonyms | 1-Boc-4-(2-aminophenoxy)-piperidine N1-BOC-4-(2''-AMINOPHENOXY)PIPERIDINE 4-(2'-AMINOPHENOXY)PIPERIDINE, N1-BOC PROTECTED tert-butyl4-(2-aminophenoxy)piperidine-1-carboxylate tert-butyl 4-(2-aminophenoxy)piperidine-1-carboxylate TERT-BUTYL 4-(2-AMINOPHENOXY)PIPERIDINE-1-CARBOXYLATE TERT-BUTYL 4-(2-AMINOPHENOXY)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE tert-butyl 4-(2-aminophenoxy)tetrahydro-1(2H)-pyridinecarboxylate tert-Butyl 4-(2-aminophenoxy)piperidine-1-carboxylate, 2-{[1-(tert-Butoxycarbonyl)piperidin-4-yl]oxy}aniline |
| CAS | 690632-14-5 |
| InChI | InChI=1/C16H24N2O3/c1-16(2,3)21-15(19)18-10-8-12(9-11-18)20-14-7-5-4-6-13(14)17/h4-7,12H,8-11,17H2,1-3H3 |
690632-14-5 - Physico-chemical Properties
| Molecular Formula | C16H24N2O3 |
| Molar Mass | 292.37 |
| Density | 1.14g/cm3 |
| Melting Point | 71 °C |
| Boling Point | 421.2°C at 760 mmHg |
| Flash Point | 208.6°C |
| Vapor Presure | 2.64E-07mmHg at 25°C |
| Refractive Index | 1.552 |
690632-14-5 - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R25 - Toxic if swallowed R36 - Irritating to the eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| Hazard Note | Harmful |
690632-14-5 - Introduction
tert-butyl4-(2-aminophenoxy)piperidine-1-carboxylate is a compound with the formula C16H25N2O3, which is a white solid.
The compound has the following properties:
-Melting point: about 60-65 degrees Celsius
-Boiling point: about 410 degrees Celsius
-Solubility: Soluble in organic solvents such as methanol, ethanol and chloroform, insoluble in water.
tert-butyl4-(2-aminophenoxy)piperidine-1-carboxylate are mainly used as intermediates in organic synthesis and are commonly used in pharmaceutical synthesis and chemical research. It can be further modified into various physiologically active compounds.
The method for preparing tert-butyl4-(2-aminophenoxy)piperidine-1-carboxylate is generally synthesized by chemical reaction, and the specific steps are as follows:
1. reacting 2-aminophenol with tert-butyl magnesium bromide (tert-butylmagnesium bromide) to give 4-(2-aminophenoxy) quinoline.
2. 4-(2-aminophenoxy) quinoline reacts with tert-butyl formate to generate tert-butyl4-(2-aminophenoxy)piperidine-1-carboxylate.
For safety information on this compound, note the following:
-The compound may be irritating and should avoid skin contact and inhalation.
-In the operation, should take appropriate protective measures, such as wearing protective gloves and goggles.
-When storing, it should be sealed and kept away from fire and oxidizing agents.
-When using or handling the compound, the relevant safe operating regulations and procedures should be followed.
The compound has the following properties:
-Melting point: about 60-65 degrees Celsius
-Boiling point: about 410 degrees Celsius
-Solubility: Soluble in organic solvents such as methanol, ethanol and chloroform, insoluble in water.
tert-butyl4-(2-aminophenoxy)piperidine-1-carboxylate are mainly used as intermediates in organic synthesis and are commonly used in pharmaceutical synthesis and chemical research. It can be further modified into various physiologically active compounds.
The method for preparing tert-butyl4-(2-aminophenoxy)piperidine-1-carboxylate is generally synthesized by chemical reaction, and the specific steps are as follows:
1. reacting 2-aminophenol with tert-butyl magnesium bromide (tert-butylmagnesium bromide) to give 4-(2-aminophenoxy) quinoline.
2. 4-(2-aminophenoxy) quinoline reacts with tert-butyl formate to generate tert-butyl4-(2-aminophenoxy)piperidine-1-carboxylate.
For safety information on this compound, note the following:
-The compound may be irritating and should avoid skin contact and inhalation.
-In the operation, should take appropriate protective measures, such as wearing protective gloves and goggles.
-When storing, it should be sealed and kept away from fire and oxidizing agents.
-When using or handling the compound, the relevant safe operating regulations and procedures should be followed.
Last Update：2024-04-09 21:54:55
