69097-97-8

69097-97-8 - Names and Identifiers

Name	7-Hydroxy-2-(p-hydroxyphenyl)-2,3-dihydro-4H-1-benzopyran-3-one
Synonyms	DL-Liquiritigenin Liquiritigenin Standard 7,4'-dihydroxy-dihydroflavone 7-Hydroxy-2-(p-hydroxyphenyl)chroman-3-one 7-Hydroxy-2-(p-hydroxyphenyl)-2,3-dihydro-4H-1-benzopyran-3-one 7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one 2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CAS	69097-97-8

69097-97-8 - Physico-chemical Properties

Molecular Formula	C15H12O4
Molar Mass	256.25
Density	1.386
Melting Point	169-170℃
Solubility	Acetone (Slightly), DMSO (Slightly, Sonicated), Ethanol (Slightly, Sonicated)
Appearance	Solid
Color	Pale Yellow to Yellow
Storage Condition	-20°C Freezer, Under inert atmosphere

69097-97-8 - Reference

Reference

1. MI, Zhenqing. Study on HPLC fingerprint of Guilong kechuanning capsules and determination of seven active components [J]. China pharmacist, 2020, v.23(05):162-166.
2. [IF = 5.34] Jing Zhang et al."Application of" spider-web "mode in discovery and identification of Q-markers from Xuefu Zhuyu capsule." Phytopedicine. 2020 Oct;77:153273
3. [IF = 4.36] Li Lin et al."Study on the alloy of fangshi Gutong capsule on rheumatoid arthritis through integrating network pharmacology and experimental exploration." J Ethnopharmacol. 2021 Nov;280:114471
4. [IF = 4.36] Li-Mei Feng et al."An integrated strategy for discovering effective components of Shaoyao Gancao decoction for treating neuropathic pain by the combination of partial least-squares regression and multi-index comprehensive method."J Ethnopharmacol. 2020 Oc
5. [IF=3.69] Qian Zhang et al."Qishen Granule alleviates endoplasmic reticulum stress-induced myocardial apoptosis through IRE-1-CRYAB pathway in myocardial ischemia."J Ethnopharmacol. 2020 Apr;252:112573
6. [IF=1.885] Xia Wenxin et al."Study on the Spectrum-Effect Relationship of the Traditional Effect of Saponins in Glycyrrhiza uralensis Fisch."Int J Anal Chem. 2021;2021:6617033

69097-97-8 - Introduction

7-Hydroxy-2-(p-hydroxyphenyl)-2, also known as 7-hydroxy-(p-hydroxyphenyl)-2,3-dihydro-4H-benzo [1,4] Pyran-3-one, is an organic compound.

Nature:
-Appearance: White crystalline solid
-Melting point: 215-217 ° C
-Molecular formula: C15H12O4
-Molecular weight: 256.25g/mol

Use:
- 7-Hydroxy-2-(p-hydroxyphenyl)-2, inhibits some inflammation-related enzymes, such as 5-LOX and COX-2, thereby having an anti-inflammatory effect on the inflammatory process.
-As an antioxidant, it can neutralize free radicals and protect cells from oxidative stress.
- 7-Hydroxy-2-(p-hydroxyphenyl)-2, it also has antibacterial effect and has inhibitory effect on certain bacteria and fungi.

Method:
- 7-Hydroxy-2-(p-hydroxyphenyl)-2 can be prepared by a synthetic method. A common synthetic route is through the condensation reaction of 2,4-dihydroxybenzaldehyde and 2-acetylacetone, followed by cyclization to obtain the target product.

Safety Information:
-There are limited studies on the toxicity and safety of 7-Hydroxy-2-(p-hydroxyphenyl)-2, and more studies are needed to fully evaluate its safety.
-When using, follow laboratory safety regulations and avoid contact with skin and eyes.
-If taken by mistake or inhaled, seek medical attention immediately.

Last Update：2024-04-10 22:29:15