697230-91-4

697230-91-4 - Names and Identifiers

Name	3aH-Indazol-3-amine, 4-fluoro-
Synonyms	4-Fluoro-3aH-indazol-3-amine 3aH-Indazol-3-amine, 4-fluoro- 3aH-Indazol-3-aMine, 4-fluoro- 3aH-Indazol-3-amine,4-fluoro-(9CI)
CAS	697230-91-4

697230-91-4 - Physico-chemical Properties

Molecular Formula	C7H6FN3
Molar Mass	151.14
Density	1.55±0.1 g/cm3(Predicted)
Boling Point	290.5±50.0 °C(Predicted)
pKa	6.53±0.40(Predicted)
Storage Condition	2-8°C

697230-91-4 - Introduction

3aH-Indazol-3-amine, 4-fluoro-is an organic compound with the chemical formula C7H6FN3. It is a white solid with a strong ammonia odor. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White solid.
-Solubility: Soluble in organic solvents, such as dimethyl amide, dichloromethane and ethanol.
-Melting point: approximately in the range of 160-165°C.
-Stability: relatively stable at room temperature, but avoid contact with oxidants.

Use:
3aH-Indazol-3-amine, 4-fluoro-is an intermediate compound commonly used in organic synthesis. It can be used as a raw material for the synthesis of compounds such as drugs, pesticides, pigments and dyes.

Preparation Method:
There are many ways to prepare 3aH-Indazol-3-amine, 4-fluoro-, the following is a common method:
1. First, the n-peralkylation reaction of p-nitroaniline and n-propionitrile at 0°C is used to generate the nitrogen cation of aniline.
2. Then, the generated nitrogen cation reacts with hydrogen fluoride to generate 3-fluoroaniline.
3. Finally, 3-fluoroaniline and indazole are subjected to amination reaction, and heated in the presence of hydrochloric acid to generate 3aH-Indazol-3-amine, 4-fluoro-.

Security Information:
- 3aH-Indazol-3-amine, 4-fluoro-may have a certain teratogenic effect on the human body, so it is necessary to follow certain safety operation specifications during use.
-Appropriate precautions such as gloves, goggles and protective clothing should be taken when handling the compound.
-Avoid contact with skin, eyes and mucous membranes. In case of contact, rinse immediately with plenty of water and seek medical help.
-During storage and use, avoid contact with oxidants and combustibles to prevent accidents such as fire or explosion.
- 3aH-Indazol-3-amine, 4-fluoro-should not be discharged directly into the environment and should be properly treated and disposed of to avoid pollution to the environment.

Last Update：2024-04-09 21:01:54