6H-3a,6-Epoxyazulen-6-ol,1,2,3,4,5,8a-hexahydro-
Curcumenol
CAS: 19431-84-6
Molecular Formula: C15H22O2
6H-3a,6-Epoxyazulen-6-ol,1,2,3,4,5,8a-hexahydro- - Names and Identifiers
6H-3a,6-Epoxyazulen-6-ol,1,2,3,4,5,8a-hexahydro- - Physico-chemical Properties
| Molecular Formula | C15H22O2 |
| Molar Mass | 234.33 |
| Density | 1.10 |
| Melting Point | 113-115 °C |
| Boling Point | 349.3±42.0 °C(Predicted) |
| Specific Rotation(α) | (c, 2.127 in CHCl3)-32.26 |
| Flash Point | 146.7°C |
| Solubility | Easily soluble in chloroform and ether, soluble in ethanol, slightly soluble in petroleum ether, almost insoluble in water. |
| Vapor Presure | 2.88E-06mmHg at 25°C |
| Appearance | Colorless needle crystal (ethyl acetate) |
| pKa | 12.38±0.60(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.553 |
| MDL | MFCD00272163 |
| Physical and Chemical Properties | White needle crystal, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Curcuma. |
6H-3a,6-Epoxyazulen-6-ol,1,2,3,4,5,8a-hexahydro- - Reference
| Reference Show more | 1. Pan Chunlin, Fan Heng. Study on Gas Fingerprint of Turmeric Volatile Oil Components. 2. Wang Mao, Ye Lihong. Study on Inhibitory Effects of Monomers and Compatibility in Qizhu Prescription on Human Gastric Cancer Cell MGC-803 [J]. Journal of Traditional Chinese Medicine, 2012, 40(004):26-28. 3. Wang Fengyun, li Weihong. Preparation and Anti-tumor Activity of Curcumol Solid Lipid Nanoparticles [J]. Chinese Medicine, 2020,042 (005):1114-1119. 4. Zhou Wei, Han Jinglan, Li Taihong. Effect of Curcumol on Invasion, Migration and Epithelial-mesenchymal Transformation of Non-small Cell Lung Cancer A549 Cells [J]. Journal of Traditional Chinese Medicine, 2019, 34(008):1675-1680. 5. Hao Min, Lu Tulin, Mao Chunqin, et al. UPLC fingerprint and multi-component content determination of three kinds of Wenyujin rhizome processed products [J]. Chinese Journal of Traditional Chinese Medicine 2018 43(11). 6. Hong Zongchao, Wu Hezhen, Yang Yanfang, qualitative and Quantitative Analysis of Volatile Oil Components from Curcuma longa Based on GC-MS and GC Technology [J]. Zhongnan Pharmacy, 2019, 17(03):112-120. 7. Feng Chenfang, Cao Wenfu, Ye Feng. Study on Mechanism of Curcuma Curcuma-containing Serum Inhibiting Expression of Glil and β-catenin in Rat HSC [J]. Journal of Chongqing Medical University, 2017, 042(003):308-314. 8. Zhang Xiaoyun, Cui Xiaobing, He Ruixin, Wang Qi, Xu Yadie, Ji Jing, Li Qiutong, Cao Jie, Tang Tingting, Fang Yutong, Cheng Jianming. Based on fingerprint and chemical pattern recognition method, the origin of Curcuma zedoary in Wenjing Decoction is optimized [J]. Journal of Liaoning University of Traditional Chinese Medicine, 2021,23(01):35-39. 9. [IF = 5.64] Wu Dousheng et al."Oleanolic Acid Induces the Type III Secretion System of Ralstonia solanacearum." Front Microbiol. 2015 Dec;0:1466 10. [IF = 2.727] Shen Song et al."Spectrum-effect relationship analysis by binary chromatographic fingerprint to identify components responsible for the antibacterial activity of the essential oil from Curcumae wenyujin." Int J Food Prop. 2018;21(1):546-556 11. [IF = 3.906] Wen Sheng et al."Curcumol inhibits the malignant progression of prostate cancer and regulates the PDK1/AKT/mTOR pathway by targeting miR-9." Oncol Rep.2021 Nov;46(5):1-11 12. [IF = 7.658] Mingyue Zhou et al."Atomic zinc sites with hierarchical porous carbon for high-throughput chemical screening with high loading capacity and stability." Pharmacol Res. 2022 Mar;:106154 |
6H-3a,6-Epoxyazulen-6-ol,1,2,3,4,5,8a-hexahydro- - Introduction
Curcumenol, also known as syringol, is an organic compound with the chemical formula C10H12O. It is a colorless liquid with a special aromatic taste.
Curcumenol has a variety of uses. First of all, it is widely used in the fragrance industry and is often used as a flavoring agent to add aroma to food, beverages and oral care products. Secondly, in the field of medicine, Curcumenol has pharmacological effects such as antibacterial, antioxidant and analgesic, and is often used to make antibacterial mouth lotions and analgesic drugs. In addition, Curcumenol can also be used to make cosmetics, such as lipstick, perfume and so on.
There are many ways to make Curcumenol. One of the main preparation methods is through the phenol-formaldehyde condensation reaction, the condensation of phenol and formaldehyde to produce phenhydralone, and then through the reduction reaction to obtain Curcumenol. In addition, Curcumenol can also be obtained by extracting from the natural plant zedoary.
When using curcurcurcumenol, you need to pay attention to some safety information. Curcumenol is irritating and may cause irritation to the eyes and skin, please avoid direct contact. Wear appropriate protective equipment such as gloves and goggles during use. In addition, Curcumenol is flammable and should be kept away from open flames and high temperatures and stored in a cool and dry place. If you eat by mistake or have an accident, you should seek medical assistance immediately.
Curcumenol has a variety of uses. First of all, it is widely used in the fragrance industry and is often used as a flavoring agent to add aroma to food, beverages and oral care products. Secondly, in the field of medicine, Curcumenol has pharmacological effects such as antibacterial, antioxidant and analgesic, and is often used to make antibacterial mouth lotions and analgesic drugs. In addition, Curcumenol can also be used to make cosmetics, such as lipstick, perfume and so on.
There are many ways to make Curcumenol. One of the main preparation methods is through the phenol-formaldehyde condensation reaction, the condensation of phenol and formaldehyde to produce phenhydralone, and then through the reduction reaction to obtain Curcumenol. In addition, Curcumenol can also be obtained by extracting from the natural plant zedoary.
When using curcurcurcumenol, you need to pay attention to some safety information. Curcumenol is irritating and may cause irritation to the eyes and skin, please avoid direct contact. Wear appropriate protective equipment such as gloves and goggles during use. In addition, Curcumenol is flammable and should be kept away from open flames and high temperatures and stored in a cool and dry place. If you eat by mistake or have an accident, you should seek medical assistance immediately.
Last Update：2024-04-09 20:52:54
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Spot supply
Product Name: Curcumenol Visit Supplier Webpage Request for quotationCAS: 19431-84-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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