7-(Trifluoromethyl)quinoline
7-trifluoromethylquinoline
CAS: 325-14-4
Molecular Formula: C10H6F3N
7-(Trifluoromethyl)quinoline - Names and Identifiers
| Name | 7-trifluoromethylquinoline |
| Synonyms | 7-Trrfluoromethylquinoline 7-trifluoromethylquinoline 7-(Trifluoromethyl)quinoline 7-(TRIFLUOROMETHYL)QUINOLINE quinoline, 7-(trifluoromethyl)- Quinoline, 7-(trifluoromethyl)- |
| CAS | 325-14-4 |
| InChI | InChI=1/C10H6F3N/c11-10(12,13)8-4-3-7-2-1-5-14-9(7)6-8/h1-6H |
7-(Trifluoromethyl)quinoline - Physico-chemical Properties
| Molecular Formula | C10H6F3N |
| Molar Mass | 197.16 |
| Density | 1.311±0.06 g/cm3(Predicted) |
| Melting Point | 65-67°C |
| Boling Point | 236.6℃ (762 Torr) |
| Flash Point | 101.2°C |
| Vapor Presure | 0.0494mmHg at 25°C |
| pKa | 2.55±0.14(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.54 |
7-(Trifluoromethyl)quinoline - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
7-(Trifluoromethyl)quinoline - Introduction
7-trifluoromethylquinoline(7-trifluoromethylquinoline) is an organic compound with the molecular formula C10H5F3N. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 7-trifluoromethylquinoline is a colorless to light yellow crystal or powder.
-Solubility: It is soluble in common organic solvents, such as alcohols, ethers and chlorinated hydrocarbons.
Use:
-Chemical synthesis: 7-trifluoromethylquinoline can be used as a reagent in organic synthesis, especially in the synthesis of drugs and pesticides.
-Drug research: It has certain research value in the field of medicine, and may have antibacterial, anti-inflammatory and anti-tumor activities.
Method:
7-trifluoromethylquinoline can be synthesized:
-Synthesized by introducing a trifluoromethyl group in quinoline. A common method is to use trifluoromethyl magnesium bromide or trifluoromethyl copper iodide in the reaction of hydrocarbons.
-It can also be synthesized by introducing a nitro group into quinoline, then reducing it to an amino group, and then performing a trifluoromethylation reaction.
Safety Information:
7-trifluoromethylquinoline is a relatively safe compound under reasonable conditions of use and storage. However, the following safety precautions are required for any chemical:
-Eye and skin contact: Avoid contact with skin and eyes. If contact occurs, wash immediately with plenty of water.
-Inhalation and Ingestion: Avoid inhaling powder. If you ingest or inhale large amounts, you should seek medical attention as soon as possible.
-Flame and explosion risk: It is combustible and should be kept away from open flames and high temperatures.
This information is for reference. If 7-trifluoromethylquinoline is used in a laboratory or industrial production, please ensure that it is used in a safe environment, follow the relevant operating procedures and safety guidelines according to the requirements of the specific application.
Nature:
-Appearance: 7-trifluoromethylquinoline is a colorless to light yellow crystal or powder.
-Solubility: It is soluble in common organic solvents, such as alcohols, ethers and chlorinated hydrocarbons.
Use:
-Chemical synthesis: 7-trifluoromethylquinoline can be used as a reagent in organic synthesis, especially in the synthesis of drugs and pesticides.
-Drug research: It has certain research value in the field of medicine, and may have antibacterial, anti-inflammatory and anti-tumor activities.
Method:
7-trifluoromethylquinoline can be synthesized:
-Synthesized by introducing a trifluoromethyl group in quinoline. A common method is to use trifluoromethyl magnesium bromide or trifluoromethyl copper iodide in the reaction of hydrocarbons.
-It can also be synthesized by introducing a nitro group into quinoline, then reducing it to an amino group, and then performing a trifluoromethylation reaction.
Safety Information:
7-trifluoromethylquinoline is a relatively safe compound under reasonable conditions of use and storage. However, the following safety precautions are required for any chemical:
-Eye and skin contact: Avoid contact with skin and eyes. If contact occurs, wash immediately with plenty of water.
-Inhalation and Ingestion: Avoid inhaling powder. If you ingest or inhale large amounts, you should seek medical attention as soon as possible.
-Flame and explosion risk: It is combustible and should be kept away from open flames and high temperatures.
This information is for reference. If 7-trifluoromethylquinoline is used in a laboratory or industrial production, please ensure that it is used in a safe environment, follow the relevant operating procedures and safety guidelines according to the requirements of the specific application.
Last Update：2024-04-09 19:05:49
