7-(beta-D-Glucopyranosyloxy)-2H-1-benzopyran-2-one
Skimmin
CAS: 93-39-0
Molecular Formula: C15H16O8
7-(beta-D-Glucopyranosyloxy)-2H-1-benzopyran-2-one - Names and Identifiers
7-(beta-D-Glucopyranosyloxy)-2H-1-benzopyran-2-one - Physico-chemical Properties
| Molecular Formula | C15H16O8 |
| Molar Mass | 324.28 |
| Density | 1.588 |
| Melting Point | 221-222℃ |
| Boling Point | 422.63°C (rough estimate) |
| Specific Rotation(α) | D18 -80° (c = 10 in pyridine) |
| Solubility | Soluble in methanol, DMSO |
| Appearance | White powder or crystal |
| pKa | 12.73±0.70(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.5500 (estimate) |
| MDL | MFCD00017710 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Tripterygium wilfordii, taro, claw gold. |
7-(beta-D-Glucopyranosyloxy)-2H-1-benzopyran-2-one - Reference
| Reference Show more | 1. Lu Senhua, Li Qiang, fan Wenyan, Chen Yu, Liu Jicheng. Evaluation of quality of xiaoliuteng from different habitats by HPLC characteristic fingerprint combined with Chemometrics [J]. Modern Chinese medicine research and practice, 2020,34(06):52-56. |
7-(beta-D-Glucopyranosyloxy)-2H-1-benzopyran-2-one - Reference Information
| Introduction | , also known as 7-o-β-d-glucopyranosyloxycoumarin, enroside is widely distributed in various plants and citrus fruits, and has the activity of treating renal insufficiency. At present, the drugs for the treatment of renal insufficiency are mainly Benazepril and Losartan, but they mainly rely on imports, are expensive, and have large toxic and side effects, such as hyperkalemia, Cough is serious, and the effect of lowering blood pressure is too weak.|
| preparation | a method for the preparation of enroside, characterized in that the method consists of the following steps: (1) take the whole plant of horseshoe gold, extract 3 times with acetone solution at room temperature, 10-30 minutes each time, combine the extract, reduce pressure and concentrate to extract; (2) the extract was subjected to 15-18 countercurrent extraction with a mixture of ethyl acetate and methanol in a ratio of 10: 1, the extract was combined, and the solvent was recovered under reduced pressure to obtain the extract. (3) the extract was dispersed by adding water, through the polyamide resin column, 30-60% ethanol elution, the eluent is concentrated to obtain crude product; (4) the crude product is dissolved with methanol, and the sample is applied to the medium pressure chromatography column with silica gel mesh 200-300, the mixture was eluted with methanol-dichloromethane, and the eluate of the target component segment was collected, filtered and concentrated, and dried at low temperature to obtain enroside. |
| biological activity | , can inhibit the deposition of immune complexes, has anti-inflammatory activity.|
| Use | rotiferin is a useful research chemical with neuroprotective effects. Enroside has the effect of protecting renal function and anti-inflammatory. for content determination/identification/pharmacological experiments. Pharmacological Efficacy: has a better therapeutic effect on diabetic nephropathy |
Last Update：2024-04-09 19:05:15
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Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Skimmin Visit Supplier Webpage Request for quotationCAS: 93-39-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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