7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone
7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone
CAS: 34564-13-1
Molecular Formula: C21H20N2O3
7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone - Names and Identifiers
7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone - Physico-chemical Properties
| Molecular Formula | C21H20N2O3 |
| Molar Mass | 348.4 |
| In vitro study | EMI48 inhibits EGFR ex19del/T790M/C797S and EGFR L858R/T790M/C797S. EMI48 can be used in the research of mutant EGFR-associated, drug-resistant non-small-cell lung cancer (NSCLC). |
7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone - Reference Information
| Biological activity | EMI48 is a derivative of EMI1, EMI48 has greater potency for mutant EGFR than EMI1. EMI48 inhibits EGFR triple mutants. |
| target | EGFR L858R/T790M/C797S EGFR del19 T790M C797S |
| in vitro study | EMI48 inhibits EGFR ex19del/T790M/C797S and EGFR L858R/T790M/C797S. EMI48 can be used in the research of human EGFR-associated, drug-resistant non-small-cell lung cancer (NSCLC). |
Last Update：2024-04-10 22:29:15
