Molecular Formula | C21H20O10 |
Molar Mass | 432.38 |
Density | 1.642±0.06 g/cm3 (20 ºC 760 Torr) |
Boling Point | 784.0±60.0 °C(Predicted) |
Solubility | Soluble in methanol, ethanol, water and other solvents, insoluble in petroleum ether, chloroform, dichloromethane and other solvents. |
Appearance | Yellow crystal |
pKa | 5.92±0.40(Predicted) |
Storage Condition | 2-8°C(protect from light) |
MDL | MFCD22125001 |
Physical and Chemical Properties | Yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from Scutellaria baicalensis, wood butterfly. |
In vitro study | Oroxin A (0.5- 100 μM; 24 hours) significantly increases the PPARγ transcription level and exhibits the strongest activation with 50 μM in HEK-293t cells. |
Reference Show more | 1. Zhang Ning, Gao Xia, Zhou Yu, et al. Rapid analysis of chemical constituents in Xingbei Zhike granules by UPLC-Q-TOF-MS/MS [J]. Chinese Journal of Traditional Chinese Medicine, 2018, 43(22):4439-4449. 2. [IF = 3.969] Pei Tianlin et al."Characterization of UDP-glycosyltransferase family members reports. Bmc Genomics. 2022 Dec;23(1):1-14 |
biological activity | Oroxin A is Oroxylum indicum(L.) the main component of the Kurz (lagerstroemia) seed extract (OISE) activates PPAR gamma by binding to the PPAR gamma protein ligand binding domain. Oroxin A inhibits the activity and antioxidant capacity of α-glucosidase α-glucosidase. Oroxin A has anti-cancer potential. |
Use | camitoside A has antitussive and expectorant effects. for content determination/identification/pharmacological experiments. Pharmacological effects: with antioxidant, anti-inflammatory effects. |