Molecular Formula | C7H7ClN2O3S |
Molar Mass | 234.66 |
Density | 1.81±0.1 g/cm3(Predicted) |
Melting Point | >180°C (dec.) |
Boling Point | 498.9±45.0 °C(Predicted) |
Flash Point | 255.5°C |
Solubility | Aqueous Acid (Slightly, Heated), DMSO (Slightly, Heated, Sonicated) |
Vapor Presure | 2.61E-11mmHg at 25°C |
Appearance | Solid |
Color | Pale Yellow |
pKa | 1.87±0.50(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.735 |
Use | Used as cephalosporin drug intermediates |
Hazard Symbols | Xi - Irritant |
Hazard Class | IRRITANT |
overview | 7-amino -3-chloro -3-cephalocyclic -4-carboxylic acid (abbreviated as 7-ACCA),7-ACCA is the key intermediate for the synthesis of the second-generation cephalosporin cefaclor. my country successfully developed cefaclor raw materials in the 2090 s, but the synthesis of raw materials has not yet achieved large-scale industrialization. The domestic production of cefaclor preparations mainly relies on imported foreign raw materials for repackaging. The main reason is 7-ACCA The synthesis process is not yet mature. |
biological activity | 7-Amino-3-chloro cephalosporanic acid (7-ACCA) is an important intermediate for the synthesis of the second generation cephalosporin cefaclor Cefaclor (HY-B0198). |
use | as an intermediate for cephalosporins |