7-BENZYLOXY-4-CHLORO-6-METHOXY-QUINAZOLINE

7-BENZYLOXY-4-CHLORO-6-METHOXY-QUINAZOLINE - Names and Identifiers

Name	7-Benzyloxy-4-chloro-6-methoxyquinazoline
Synonyms	7-Benzyloxy-4-chloro-6-methoxy-quizoline 4-chloro-7-benzyloxy-6-methoxyquinazoline 4-Chloro-6-methoxy-7-benzyloxyquinazoline 7-Benzyloxy-4-chloro-6-methoxyquinazoline 4-chloro-7-benzyloxy -6-Methoxyquinazoline 7-BENZYLOXY-4-CHLORO-6-METHOXY-QUINAZOLINE 7-(benzyloxy)-4-chloro-6-methoxyquinazoline 4-chloro-6-methoxy-7-(phenylmethoxy)quinazoline Quinazoline, 4-chloro-6-Methoxy-7-(phenylMethoxy)-
CAS	162364-72-9
EINECS	810-462-2
InChI	InChI=1/C16H13ClN2O2/c1-20-14-7-12-13(18-10-19-16(12)17)8-15(14)21-9-11-5-3-2-4-6-11/h2-8,10H,9H2,1H3

7-BENZYLOXY-4-CHLORO-6-METHOXY-QUINAZOLINE - Physico-chemical Properties

Molecular Formula	C16H13ClN2O2
Molar Mass	300.74
Density	1.303±0.06 g/cm3(Predicted)
Boling Point	452.1±40.0 °C(Predicted)
Flash Point	227.198°C
Vapor Presure	0mmHg at 25°C
pKa	0.72±0.30(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.639

7-BENZYLOXY-4-CHLORO-6-METHOXY-QUINAZOLINE - Introduction

Boc benzyloxyquinazoline, also known as Boc benzyloxyquinazoline, is an organic compound. Its chemical formula is C13H12ClNO2.

In terms of nature, it is a white to pale yellow crystal with a taste of nicotinic acid ester. It is stable at room temperature, but may decompose under high temperature or strong light. It is soluble in solvents.

The main use of this compound is as a reagent in organic synthesis. It can be used to synthesize a variety of bioactive compounds, such as drugs, pesticides and biomarkers. It can also be used as a catalyst and as a ligand for transition metal complexes.

in terms of preparation method, P-chlorobenzoic acid methyl ester can be obtained by reacting p-methoxybenzoic acid with phosphorus chloride pentachloride, and then reacted with 2-aminopyridine to generate 4-chloro-6-methoxyquinazoline, finally, the target product was obtained by oxidation with benzyl ammonium bromide.

When using this compound, you need to pay attention to safety matters. It may be irritating to the skin, eyes and respiratory system and direct contact should be avoided. Wear appropriate protective gloves and glasses and operate in a well-ventilated area. If exposed or inhaled, wash the affected area immediately and seek medical help. In addition, the compound should be stored and handled properly to avoid incompatibility with other chemicals.

Last Update：2024-04-10 22:30:50