7-BROMO-1H-INDOLE-2,3-DIONE
7-Bromoisatin
CAS: 20780-74-9
Molecular Formula: C8H4BrNO2
7-BROMO-1H-INDOLE-2,3-DIONE - Names and Identifiers
| Name | 7-Bromoisatin |
| Synonyms | 7-Bromoisatin 7-BROMO-ISATIN 7-BROMO-2,3-DIOXOINDOLINE 7-bromoindoline-2,3-dione 7-BROMOINDOLINE-2,3-DIONE 7-Bromoindole-1H-2,3-dione 7-bromo-1H-indole-2,3-dione 7-BROMO-1H-INDOLE-2,3-DIONE 7-BROMOINDOLE-3-CARBOXALDEHYDE 7-Bromoindoline-2,3-dione, 7-Bromo-1H-indole-2,3-dione |
| CAS | 20780-74-9 |
| EINECS | 625-256-6 |
| InChI | InChI=1/C8H4BrNO2/c9-5-3-1-2-4-6(5)10-8(12)7(4)11/h1-3H,(H,10,11,12) |
7-BROMO-1H-INDOLE-2,3-DIONE - Physico-chemical Properties
| Molecular Formula | C8H4BrNO2 |
| Molar Mass | 226.03 |
| Density | 1.826±0.06 g/cm3(Predicted) |
| Melting Point | 191-198 °C |
| Solubility | Slightly soluble. |
| Appearance | Solid |
| Color | Orange to Amber to Dark red |
| pKa | 8.69±0.20(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.649 |
| MDL | MFCD00774354 |
7-BROMO-1H-INDOLE-2,3-DIONE - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
| Hazard Note | Irritant |
7-BROMO-1H-INDOLE-2,3-DIONE - Introduction
7-Bromoisatin is a brominated organic compound. Its chemical formula is C9H5BrNO2. The following is its nature, use, preparation and safety information:
Nature:
1. Appearance: White or yellowish crystalline solid.
2. Melting Point: about 100-101 ℃.
3. Boiling point: about 354 ℃.
4. Solubility: Soluble in organic solvents (such as dimethyl sulfoxide, ether).
Use:
1. 7-Bromoisatin is commonly used as catalyst and intermediate in organic synthesis.
2. It is also used in some medical fields, for example, as a precursor of anti-inflammatory drugs and anti-cancer drugs.
Method:
There are many preparation methods for 7-Bromoisatin. The following is one of the commonly used methods:
7-Bromoisatin is generated by the reaction of 2,3-dioxoindoline and bromoacetic acid.
Safety Information:
1. 7-Bromoisatin may be irritating to the eyes, skin and respiratory system. Therefore, wear appropriate personal protective equipment during use, avoid contact with skin and eyes, and ensure good ventilation.
2. During storage and use, avoid contact with combustibles and oxidants to prevent the risk of fire or explosion.
3. If you accidentally inhale or come into contact with 7-Bromoisatin, you should immediately go to a fresh air or rinse with water, and seek medical help.
4. Please store properly, away from children and fire. Follow proper laboratory procedures to ensure safe use.
Please use and handle 7-Bromoisatin with caution and follow appropriate safety and environmental protection measures.
Nature:
1. Appearance: White or yellowish crystalline solid.
2. Melting Point: about 100-101 ℃.
3. Boiling point: about 354 ℃.
4. Solubility: Soluble in organic solvents (such as dimethyl sulfoxide, ether).
Use:
1. 7-Bromoisatin is commonly used as catalyst and intermediate in organic synthesis.
2. It is also used in some medical fields, for example, as a precursor of anti-inflammatory drugs and anti-cancer drugs.
Method:
There are many preparation methods for 7-Bromoisatin. The following is one of the commonly used methods:
7-Bromoisatin is generated by the reaction of 2,3-dioxoindoline and bromoacetic acid.
Safety Information:
1. 7-Bromoisatin may be irritating to the eyes, skin and respiratory system. Therefore, wear appropriate personal protective equipment during use, avoid contact with skin and eyes, and ensure good ventilation.
2. During storage and use, avoid contact with combustibles and oxidants to prevent the risk of fire or explosion.
3. If you accidentally inhale or come into contact with 7-Bromoisatin, you should immediately go to a fresh air or rinse with water, and seek medical help.
4. Please store properly, away from children and fire. Follow proper laboratory procedures to ensure safe use.
Please use and handle 7-Bromoisatin with caution and follow appropriate safety and environmental protection measures.
Last Update：2024-04-09 20:48:19
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CAS: 20780-74-9
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QQ: 3008007409
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CAS: 20780-74-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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