7-Bromo-2,3-dihydro-1H-indole
7-bromo-2,3-dihydro-1H-indole
CAS: 62813-85-8
Molecular Formula: C8H8BrN
7-Bromo-2,3-dihydro-1H-indole - Names and Identifiers
| Name | 7-bromo-2,3-dihydro-1H-indole |
| Synonyms | 7-bromoindoline 7-bromo-2,3-dihydro-1H-indole 7-Bromo-2,3-dihydro-1H-indole 1H-INDOLE,7-BROMO-2,3-DIHYDRO- 7-Bromoindoline 7-Bromo-2,3-dihydro-1H-indole in stock Factory |
| CAS | 62813-85-8 |
| InChI | InChI=1/C8H8BrN/c9-7-3-1-2-6-4-5-10-8(6)7/h1-3,10H,4-5H2 |
7-Bromo-2,3-dihydro-1H-indole - Physico-chemical Properties
| Molecular Formula | C8H8BrN |
| Molar Mass | 198.06 |
| Density | 1.514±0.06 g/cm3(Predicted) |
| Boling Point | 279.4±29.0 °C(Predicted) |
| Flash Point | 122.796°C |
| Vapor Presure | 0.004mmHg at 25°C |
| pKa | 3.39±0.20(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Refractive Index | 1.602 |
7-Bromo-2,3-dihydro-1H-indole - Introduction
7-bromo-2,3-dihydro-1H-indole is an organic compound with the chemical formula C8H8BrN. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 7-bromo-2,3-dihydro-1H-indole is a white crystalline solid.
-Melting point: about 85-88 degrees Celsius.
-Boiling point: about 280 degrees Celsius.
-Solubility: 7-bromo-2,3-dihydro-1H-indole is soluble in many organic solvents.
Use:
-Intermediate: 7-bromo-2,3-dihydro-1H-indole is an intermediate for many drugs and pesticides, which can be used to synthesize other organic compounds.
-Research: The compound is also used in the field of chemical research, such as as a reagent for organic synthesis reactions.
Preparation Method:
7-bromo-2,3-dihydro-1H-indole can be prepared by the following methods:
-Dissolve indole in a solvent, and then add a bromine atom source reagent, such as hydrobromic acid or cuprous bromide, and react for a period of time.
-Nucleophilic substitution reaction using indole and brominating agent under alkaline conditions.
-Synthesis of three-membered heterocyclic compounds using indole and bromide in the presence of sodium carbonate.
Safety Information:
- 7-bromo-2,3-dihydro-1H-indole is a harmful substance that has an irritating and corrosive effect on the eyes, skin and respiratory tract after contact.
-Wear appropriate personal protective equipment such as gloves, goggles and face shields during use or operation.
-Waste disposal shall comply with relevant laws and regulations.
Nature:
-Appearance: 7-bromo-2,3-dihydro-1H-indole is a white crystalline solid.
-Melting point: about 85-88 degrees Celsius.
-Boiling point: about 280 degrees Celsius.
-Solubility: 7-bromo-2,3-dihydro-1H-indole is soluble in many organic solvents.
Use:
-Intermediate: 7-bromo-2,3-dihydro-1H-indole is an intermediate for many drugs and pesticides, which can be used to synthesize other organic compounds.
-Research: The compound is also used in the field of chemical research, such as as a reagent for organic synthesis reactions.
Preparation Method:
7-bromo-2,3-dihydro-1H-indole can be prepared by the following methods:
-Dissolve indole in a solvent, and then add a bromine atom source reagent, such as hydrobromic acid or cuprous bromide, and react for a period of time.
-Nucleophilic substitution reaction using indole and brominating agent under alkaline conditions.
-Synthesis of three-membered heterocyclic compounds using indole and bromide in the presence of sodium carbonate.
Safety Information:
- 7-bromo-2,3-dihydro-1H-indole is a harmful substance that has an irritating and corrosive effect on the eyes, skin and respiratory tract after contact.
-Wear appropriate personal protective equipment such as gloves, goggles and face shields during use or operation.
-Waste disposal shall comply with relevant laws and regulations.
Last Update：2024-04-09 02:00:47
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CAS: 62813-85-8
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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