7-Bromo-3,4-dihydro-2H-1,4-benzoxazine

7-Bromo-3,4-dihydro-2H-1,4-benzoxazine - Names and Identifiers

Name	7-Bromo-3,4-dihydro-2H-benzo[1,4]oxazine
Synonyms	7-Bromo-3,4-dihydro-2H-1,4-benzoxazine 7-Bromo-3,4-dihydro-2H-benzo[1,4]oxazine 2H-1,4-Benzoxazine, 7-broMo-3,4-dihydro- 7-Bromo-3,4-dihydro-2H-benzo[b][1,4]oxazine
CAS	105679-22-9

7-Bromo-3,4-dihydro-2H-1,4-benzoxazine - Physico-chemical Properties

Molecular Formula	C8H8BrNO
Molar Mass	214.06
Density	1.534
Boling Point	300.4±42.0 °C(Predicted)
Flash Point	135.5 °C
pKa	3.65±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

7-Bromo-3,4-dihydro-2H-1,4-benzoxazine - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed

7-Bromo-3,4-dihydro-2H-1,4-benzoxazine - Introduction

7-Bromo-3, 4-dihydro-2H-1, 4-benzoxazine is an organic compound, also known as bromo-oxazine. The following is an introduction to some of its properties, uses, formulation and safety information:

Nature:
-Appearance: 7-Bromo-3, 4-dihydro-2H-1, 4-benzoxazine is a white crystalline solid.
-Melting point: Its melting point is about 234-238°C.
-Solubility: It can be dissolved in some organic solvents, such as chloroform, ethanol and dichloromethane. However, the solubility in water is relatively low.

Use:
-Pharmaceutical chemistry: 7-bromo-3, 4-dihydro-2H-1, 4-benzoxazine is used as a pharmaceutical intermediate, mainly used in the synthesis of other pharmaceutical compounds.
-Industrial application: It can also be used as a reducing agent and hydrogenation agent in organic synthesis.

Preparation Method:
There are many ways to prepare 7-bromo-3, 4-dihydro-2H-1, 4-benzoxazine, one of which is commonly used by bromination of 3,4-dihydro -2H-1, 4-benzoxazine. The specific synthetic reaction conditions and procedures may vary slightly due to experimental requirements.

Safety Information:
-7-bromo-3, 4-dihydro-2H-1, 4-benzoxazine has no clear research data on the toxicity and carcinogenicity of the human body, but it should follow the routine laboratory safety operation procedures. Attention should be paid to avoid contact with skin and inhalation of its dust during operation.
-Because the solubility of the compound in water is relatively low, avoid discharging it directly into the water body to avoid pollution to the environment.
-When handling or disposing of 7-bromo-3, 4-dihydro-2H-1, 4-benzoxazine, please comply with local environmental regulations and regulations.

The above introduces some basic properties, uses, preparation methods and safety information of 7-bromo -3,4-dihydro -2H-1,4-benzoxazine.

Last Update：2024-04-09 21:04:16