7-Bromo-6-fluoroindole
7-Bromo-6-fluoro-1H-indole
CAS: 1000339-62-7
Molecular Formula: C8H5BrFN
7-Bromo-6-fluoroindole - Names and Identifiers
| Name | 7-Bromo-6-fluoro-1H-indole |
| Synonyms | 7-Bromo-6-fluoroindole 7-Bromo-6-fluoro-1H-indole 1H-Indole, 7-broMo-6-fluoro- |
| CAS | 1000339-62-7 |
| InChI | InChI=1S/C8H5BrFN/c9-7-6(10)2-1-5-3-4-11-8(5)7/h1-4,11H |
7-Bromo-6-fluoroindole - Physico-chemical Properties
| Molecular Formula | C8H5BrFN |
| Molar Mass | 214.03 |
| Density | 1.750±0.06 g/cm3(Predicted) |
| Boling Point | 315.9±22.0 °C(Predicted) |
| pKa | 14.73±0.30(Predicted) |
7-Bromo-6-fluoroindole - Introduction
6-fluoro-7-bromoindole is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-6-fluoro-7-bromoindole is an indole compound with fluorine and bromine substituents.
-It is a solid that can form light yellow crystals.
-Under normal temperature and pressure, it is stable and not volatile.
Use:
-6-fluoro-7-bromoindole can be used as an intermediate in organic synthesis.
Preparation Method:
-6-fluoro-7-bromoindole has many preparation methods, the following is one of the commonly used methods:
1. First, a bromo group is introduced into bromoindole through a nucleophilic substitution reaction.
2. Then, under the condition of bromoindole and fluorine gas reaction, the fluorine group is introduced by nuclear magnetic grinding method.
3. Finally, pure 6-fluoro-7-bromoindole was obtained by crystallization purification and drying.
Safety Information:
-Follow routine laboratory safety procedures when handling and using 6-fluoro-7-bromoindole.
-It may be toxic and dangerous to humans and the environment, so it is necessary to take appropriate protective measures, such as wearing protective gloves and glasses.
-During storage and handling, care should be taken to avoid contact with combustibles and oxidants to prevent accidents.
Please keep in mind that the information provided above is for informational purposes only. When using chemical substances, appropriate research and experiments must be carried out according to the specific situation, and correct safe operating procedures must be followed.
Last Update：2024-04-09 19:55:45
