7-Chloro-2-oxindole
7-Chloro-2-oxindole
CAS: 25369-33-9
Molecular Formula: C8H6ClNO
7-Chloro-2-oxindole - Names and Identifiers
| Name | 7-Chloro-2-oxindole |
| Synonyms | 7-Chlorooxindole 7-Chloro-2-oxindole 7-Chloro-2-Oxindole 7-Chloro-2-oxyindole 7023 7-CHLOROINDOLIN-2-ONE 7-chloro-1,3-dihydro-2H-indol-2-one 2H-Indol-2-one, 7-chloro-1,3-dihydro- 7-Chloro-1,3-dihydro-2H-indol-2-one, 7-Chloroindolin-2-one |
| CAS | 25369-33-9 |
| EINECS | 625-279-1 |
| InChI | InChI=1/C8H6ClNO/c9-6-3-1-2-5-4-7(11)10-8(5)6/h1-3H,4H2,(H,10,11) |
7-Chloro-2-oxindole - Physico-chemical Properties
| Molecular Formula | C8H6ClNO |
| Molar Mass | 167.59 |
| Density | 1.362±0.06 g/cm3(Predicted) |
| Melting Point | 221-225 °C |
| Boling Point | 341.0±42.0 °C(Predicted) |
| Flash Point | 160°C |
| Vapor Presure | 8.27E-05mmHg at 25°C |
| pKa | 13.08±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.601 |
7-Chloro-2-oxindole - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | 61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
7-Chloro-2-oxindole - Introduction
7-chloroo-2-oxindole is an organic compound with the chemical formula C8H5ClNO, structurally substituted with a chlorine atom for one hydrogen atom in the indolone molecule. The following is a description of the nature, use, manufacture and safety information of 7-Chloro-2-oxindole:
Nature:
-Appearance: 7-Chloro-2-oxindole is a white crystalline solid.
-Melting point: about 71-72 degrees Celsius.
-Solubility: Soluble in common organic solvents such as ethanol, dimethyl sulfoxide and dichloromethane.
Use:
-Chemical synthesis: 7-Chloro-2-oxindole is a commonly used intermediate in organic synthesis and can be used to synthesize other organic compounds, such as drugs, pesticides and dyes.
-Drug research: Due to its structural specificity, 7-Chloro-2-oxindole is also often used in the field of drug research.
Method:
-7-chloroo-2-oxindole There are many preparation methods, one of which is commonly used by the reaction of 7-chloroindole with pyrazine aldehyde. This reaction is usually carried out in an alcoholic solution, and Crystal separation and purification are required after the reaction.
Safety Information:
- 7-Chloro-2-oxindole is less harmful to humans and the environment under General use conditions.
-use should follow the general laboratory safety procedures, pay attention to protective measures, such as wearing gloves, goggles and protective clothing.
- 7-Chloro-2-oxindole should be stored in a sealed container, away from fire and oxidizing agents, and avoid mixing with other chemicals.
-If the skin or eyes are touched by the outside, rinse immediately with plenty of water and seek medical treatment.
Nature:
-Appearance: 7-Chloro-2-oxindole is a white crystalline solid.
-Melting point: about 71-72 degrees Celsius.
-Solubility: Soluble in common organic solvents such as ethanol, dimethyl sulfoxide and dichloromethane.
Use:
-Chemical synthesis: 7-Chloro-2-oxindole is a commonly used intermediate in organic synthesis and can be used to synthesize other organic compounds, such as drugs, pesticides and dyes.
-Drug research: Due to its structural specificity, 7-Chloro-2-oxindole is also often used in the field of drug research.
Method:
-7-chloroo-2-oxindole There are many preparation methods, one of which is commonly used by the reaction of 7-chloroindole with pyrazine aldehyde. This reaction is usually carried out in an alcoholic solution, and Crystal separation and purification are required after the reaction.
Safety Information:
- 7-Chloro-2-oxindole is less harmful to humans and the environment under General use conditions.
-use should follow the general laboratory safety procedures, pay attention to protective measures, such as wearing gloves, goggles and protective clothing.
- 7-Chloro-2-oxindole should be stored in a sealed container, away from fire and oxidizing agents, and avoid mixing with other chemicals.
-If the skin or eyes are touched by the outside, rinse immediately with plenty of water and seek medical treatment.
Last Update：2024-04-09 02:00:44
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