7-DesMethylagoMelatine
7-Desmethylagomelatine
CAS: 152302-45-9
Molecular Formula: C14H15NO2
7-DesMethylagoMelatine - Names and Identifiers
7-DesMethylagoMelatine - Physico-chemical Properties
| Molecular Formula | C14H15NO2 |
| Molar Mass | 229.2744 |
| Density | 1.183±0.06 g/cm3(Predicted) |
| Boling Point | 511.3±33.0 °C(Predicted) |
| pKa | 9.68±0.40(Predicted) |
| Storage Condition | 2-8°C |
7-DesMethylagoMelatine - Reference Information
| Overview | agomelatine impurities are impurities that occur during the synthesis of agomelatine, and are particularly important for the formulation standards of agomelatine. The agomelatine impurity is an important impurity, and its content in the final product may affect the quality of the final product agomelatine. Through a large number of experiments, combined with the relevant data, the author explored and developed that the methoxy group on the benzene ring was cleaved by heating agomelatine in acid to reflux, controlling the solvent, dosage and reaction time to obtain agomelatine impurity. |
| biological activity | 7-desmethylagomelatine is a metabolite of Agomelatine. Agomelatineis is a potent agonist of melatonin receptors (MT1 and MT2) and is also an antagonist of 5-HT2C. |
Last Update：2024-04-09 21:54:55
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CAS: 152302-45-9
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CAS: 152302-45-9
Tel: 18301782025
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