7-FLUORO-4-HYDROXY-2-METHYLQUINOLINE

7-FLUORO-4-HYDROXY-2-METHYLQUINOLINE - Names and Identifiers

Name	7-Fluoro-4-hydroxy-2-methylquinoline
Synonyms	7-FLUORO-2-METHYL-QUINOLIN-4-OL 7-fluoro-2-methylquinolin-4(1H)-one 7-FLUORO-4-HYDROXY-2-METHYLQUINOLINE 7-Fluoro-4-hydroxy-2-methylquinoline 2-Methyl-4-hydroxy-7-fluoroquinoline 7-Fluoro-2-methylquinolin-4-ol, 7-Fluoro-4-hydroxy-2-methyl-1-azanaphthalene
CAS	18529-03-8
InChI	InChI=1/C10H8FNO/c1-6-4-10(13)8-3-2-7(11)5-9(8)12-6/h2-5H,1H3,(H,12,13)

7-FLUORO-4-HYDROXY-2-METHYLQUINOLINE - Physico-chemical Properties

Molecular Formula	C10H8FNO
Molar Mass	177.18
Density	1.305
Boling Point	271.975°C at 760 mmHg
Flash Point	118.286°C
Vapor Presure	0.006mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.554

7-FLUORO-4-HYDROXY-2-METHYLQUINOLINE - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.
WGK Germany	3

7-FLUORO-4-HYDROXY-2-METHYLQUINOLINE - Introduction

It is an organic compound with the chemical formula C10H8FNO. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: Colorless crystalline solid.
-Melting point: About 70-72 ° C.
-Boiling point: About 275 ° C.
-Solubility: Soluble in most organic solvents such as ethanol, ether and chlorinated hydrocarbons. Slightly soluble in water.

Use:
-is an important organic synthesis intermediate, which has a wide range of applications in the field of medicine and pesticide.
-plays an important role in the preparation of quinoline antimalarial drugs and analgesic drugs.
-In agriculture, it can be used to synthesize high-efficiency, low-toxicity pesticides and herbicides.

Method:
-the preparation method is more complex. A common preparation method is obtained by fluorination of 2-methylquinoline, which is then reacted with sodium hydroxide to form phospholite.

Safety Information:
-(br) Appropriate safety measures should be taken during use, such as wearing protective gloves, goggles, etc.
-avoid contact with skin, eyes and respiratory tract, such as accidental contact, should immediately rinse the relevant parts with plenty of water, and consult a doctor.
-Follow chemical safety practices during storage and handling to avoid contact with incompatible substances.
-Waste disposal shall comply with local laws and regulations.

Last Update：2024-04-09 02:00:43