Name | 7-METHOXY-ISOQUINOLINE |
Synonyms | 7-METHOXY-ISOQUINOLINE Isoquinoline, 7-methoxy- 7-Methoxy-2-azanaphthalene |
CAS | 39989-39-4 |
Molecular Formula | C10H9NO |
Molar Mass | 159.18 |
Density | 1.1202 (rough estimate) |
Melting Point | 49°C |
Boling Point | 284.68°C (rough estimate) |
pKa | 5.54±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.6070 (estimate) |
Use | Uses 7-methoxyisoquinoline is a useful research chemical for organic synthesis and other chemical processes. |
Risk Codes | 22 - Harmful if swallowed |
Hazard Note | Irritant |
Downstream Products | 7-Methoxy-isoquinolin-1(2H)-one 7-METHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE 7-Hydroxyisoquinoline |
Hazard Note | Irritant |
Take a clean single-port reaction bottle, add aminoacetaldehyde diethanol and 3-methoxybenzaldehyde, pour absolute ethanol, stir the reaction liquid at room temperature, detect the reaction progress by thin layer chromatography, and end the reaction, Use 4 mol · L-1 sodium hydroxide aqueous solution to adjust the pH of the solution to about 10, heat and reflux for 4 hours, cool, precipitate the solid, filter, and recrystallize the solid with ethanol to obtain 7-methoxyisoquinoline.
use | 7-methoxyisoquinoline is a useful research chemical for organic synthesis and other chemical processes. |
preparation | the target compound 7-methoxyisoquinoline was prepared by ring-forming reaction with aminoacetaldehyde diethanol and 3-methoxybenzaldehyde as starting materials. the synthesis reaction formula of 7-methoxyisoquinoline is shown in the following figure: experimental operation: take a clean single-port reaction bottle, add aminoacetaldehyde diethanol and 3-methoxybenzaldehyde, pour in absolute ethanol, stir the reaction liquid at room temperature, detect the reaction progress by thin layer chromatography, react for 2 hours, end the reaction, adjust the pH of the solution to about 10 with 4 mol · L-1 sodium hydroxide aqueous solution, heat and reflux for 4 hours, cool, precipitate the solid, filter, and recrystallize the solid with ethanol to obtain 7-methoxyisoquinoline. |